RAB3A, Member RAS Oncogene Family (RAB3A) (N-Term), (AA 1-30) antibody

Details for Product No. ABIN658735
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Antigen
Synonyms RAB3, rab-3a, rab3a, zgc:92276, gov, d2-2, rab16, rad3d, MGC69316, MGC130815, RAB3A
Epitope
N-Term, AA 1-30
(10), (4), (3), (2), (2), (2), (1), (1), (1)
Reactivity
Human
(53), (44), (37), (15), (15), (14), (4), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Host
Rabbit
(52), (6), (1)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application
Western Blotting (WB)
(40), (20), (16), (9), (5), (3), (3), (2), (1), (1)
Pubmed 4 references available
Catalog no. ABIN658735
Quantity 400 µL
Price
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Immunogen This RAB3A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 AA from the N-terminal region of human RAB3A.
Clone RB34429
Isotype Ig
Specificity This RAB3A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human RAB3A.
Predicted Reactivity Mouse (Murine),Pig (Porcine),Monkey,Rat (Rattus)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name RAB3A
Background RAB3A is involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal.
Synonyms: Ras-related protein Rab-3A,RAB3A,
Research Area Signaling, Phospho-specific antibodies, Protein Modifications, Cell Structure, Chromatin
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Supplier Images
anti-RAB3A, Member RAS Oncogene Family (RAB3A) (N-Term), (AA 1-30) antibody RAB3A Antibody (N-term) (ABIN658735) western blot analysis in Y79 cell line lysates (35 µg/lane). This demonstrates the RAB3A antibody detected the RAB3A protein (arrow).
Background publications Lopez, Belmonte, De Blas et al.: "Membrane-permeant Rab3A triggers acrosomal exocytosis in living human sperm." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 21, Issue 14, pp. 4121-30, 2007 (PubMed).

Figueiredo, Wasmeier, Tarafder et al.: "Rab3GEP is the non-redundant guanine nucleotide exchange factor for Rab27a in melanocytes." in: The Journal of biological chemistry, Vol. 283, Issue 34, pp. 23209-16, 2008 (PubMed).

Branham, Bustos, De Blas et al.: "Epac activates the small G proteins Rap1 and Rab3A to achieve exocytosis." in: The Journal of biological chemistry, Vol. 284, Issue 37, pp. 24825-39, 2009 (PubMed).

Szodorai, Kuan, Hunzelmann et al.: "APP anterograde transport requires Rab3A GTPase activity for assembly of the transport vesicle." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 29, Issue 46, pp. 14534-44, 2009 (PubMed).

Hosts (52), (6), (1)
Reactivities (53), (44), (37), (15), (15), (14), (4), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applications (40), (20), (16), (9), (5), (3), (3), (2), (1), (1)
Conjugates (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Epitopes (10), (4), (3), (2), (2), (2), (1), (1), (1)
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