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RAB3A, Member RAS Oncogene Family (RAB3A) (N-Term) antibody

Antigen

RAB3A, Member RAS Oncogene Family (RAB3A)

Synonyms RAB3, zgc:92276, gov, d2-2, rab16, rab3a, rad3d, MGC69316, MGC130815, RAB3A, zgc:112516
Binding Site
Alternatives

N-Term

Clonality Polyclonal
Host
Alternatives

Rabbit

Reactivity
Alternatives

Human

Conjugate
Alternatives Un-conjugated
Application
Alternatives Western Blotting (WB), ELISA
4 references available
Certificates ISO 9001:2008
Catalog no. ABIN658735
Quantity 0.1 mg  (0.25 mg/ml)
Price 280.50 $   Plus shipping costs $45.00
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Additional Information

Alternative name RAB3A
Isotype Ig
Description Other names: Ras-related protein Rab-3A,RAB3A,
Characteristics Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Specificity This RAB3A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human RAB3A.
Comments

Background: RAB3A is involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal.

Application Details

Concentration 0.25 mg/ml
Purification Purified
Research Area Signaling, Phospho-specific antibodies, Protein Modifications, Cell Structure, Chromatin
Restrictions For Research Use only

Publications

Product Lopez, Belmonte, De Blas et al.: "Membrane-permeant Rab3A triggers acrosomal exocytosis in living human sperm." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 21, Issue 14, pp. 4121-30, 2007 (PubMed).

Figueiredo, Wasmeier, Tarafder et al.: "Rab3GEP is the non-redundant guanine nucleotide exchange factor for Rab27a in melanocytes." in: The Journal of biological chemistry, Vol. 283, Issue 34, pp. 23209-16, 2008 (PubMed).

Branham, Bustos, De Blas et al.: "Epac activates the small G proteins Rap1 and Rab3A to achieve exocytosis." in: The Journal of biological chemistry, Vol. 284, Issue 37, pp. 24825-39, 2009 (PubMed).

Szodorai, Kuan, Hunzelmann et al.: "APP anterograde transport requires Rab3A GTPase activity for assembly of the transport vesicle." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 29, Issue 46, pp. 14534-44, 2009 (PubMed).

Alternatives

Alternatives for antigen "RAB3A, Member RAS Oncogene Family (RAB3A)", type "Antibodies"
Hosts Rabbit (58), Goat (2), Mouse (1)
Reactivities Human (53), Rat (Rattus) (48), Mouse (Murine) (42), Dog (Canine) (22), Cow (Bovine) (19), Pig (Porcine) (19), Horse (Equine) (18), Monkey (2), Xenopus laevis (1)
Applications Immunofluorescence (IF) (32), Western Blotting (WB) (30), ELISA (13), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (8), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (6), Immunohistochemistry (IHC) (4), Immunoprecipitation (IP) (4), Immunoelectron Microscopy (IEM) (2)
Conjugates Alexa Fluor 350 (2), Alexa Fluor 488 (2), Alexa Fluor 555 (2), Alexa Fluor 647 (2), Biotin (2), Cy3 (2), Cy5 (2), Cy5.5 (2), Cy7 (2), FITC (2), Gold (2), HRP (2), PE (2), PE,Cy3 (2), PE,Cy5 (2), PE,Cy5.5 (2), PE,Cy7 (2)
Epitopes N-Term (6), AA 202-217 (3), AA 1-18 (1), C-Term (1), C-Term,pan (1)