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Details for Product No. ABIN658794

Origin Recognition Complex, Subunit 3 (ORC3) (N-Term), (AA 17-46) antibody

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Antigen
Synonyms
LAT, LATHEO, ORC3L, Orc3l, CG4088, DmORC3, DmOrc3, Dmel\\CG4088, ORC, ORC3, Orc3, l(2)49Fd, l(2)vr6, vr-6, vr6, orc3, ATORC3, F5E19.30, F5E19_30, ORIGIN RECOGNITION COMPLEX SUBUNIT 3, origin recogniti ... show more
Epitope
»Alternatives N-Term, AA 17-46
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 2 references available
Catalog no. ABIN658794
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen This ORC3L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-46 AA from the N-terminal region of human ORC3L.
Clone RB35037
Isotype Ig
Specificity This ORC3L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 16-46 amino acids from the N-terminal region of human ORC3L.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name ORC3L
Background The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Studies of a similar gene in Drosophila suggested a possible role of this protein in neuronal proliferation and olfactory memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene.
Synonyms: Origin recognition complex subunit 3,ORC3L,LATHEO, ORC3
Research Area Phospho-specific antibodies, Protein Modifications, Transcription Factors, Signaling, Chromatin, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Background publications Matsuoka, Ballif, Smogorzewska et al.: "ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage." in: Science (New York, N.Y.), Vol. 316, Issue 5828, pp. 1160-6, 2007 (PubMed).

Enjuanes, Benavente, Bosch et al.: "Genetic variants in apoptosis and immunoregulation-related genes are associated with risk of chronic lymphocytic leukemia." in: Cancer research, Vol. 68, Issue 24, pp. 10178-86, 2008 (PubMed).

Alternatives for antigen "Origin Recognition Complex, Subunit 3 (ORC3)", type "Antibodies"
Hosts (10), (9), (6), (5)
Reactivities (27), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applications (23), (9), (5), (3), (3), (2), (2), (1)
Epitopes (6), (5), (3), (2), (2), (1)
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