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MAP2K4 antibody (Mitogen-Activated Protein Kinase Kinase 4) (AA 259-287)

Details for Product anti-MAP2K4 Antibody No. ABIN658838, Supplier: Login to see New
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Antigen
Synonyms
jnkk, mek4, mkk4, sek1, jnkk1, serk1, xmek2, mapkk4, prkmk4, 142758_at, CG9738, CT27508, D-MKK4, DMKK4, Dmel\\CG9738, JNKK2, MAPKK4, MKK4, Mpk4, SEK1/MKK4, dMKK4, dMkk4, hep, CT38386, DmelCG12798, Sek ... show more
jnkk, mek4, mkk4, sek1, jnkk1, serk1, xmek2, mapkk4, prkmk4, 142758_at, CG9738, CT27508, D-MKK4, DMKK4, Dmel\\CG9738, JNKK2, MAPKK4, MKK4, Mpk4, SEK1/MKK4, dMKK4, dMkk4, hep, CT38386, DmelCG12798, Sek1, 2, JNKK, Jnkk2, Mapkk7, Mek7, Mkk7, JNKK1, MEK4, PRKMK4, SAPKK-1, SAPKK1, SEK1, SERK1, SKK1, Serk1, ARABIDOPSIS THALIANA MITOGEN-ACTIVATED PROTEIN KINASE KINASE 4, ATMEK4, ATMKK4, F19C24.26, F19C24_26, MAP KINASE KINASE 4, mitogen-activated protein kinase kinase 4, MKK4A-l, map2k4, zgc:136500 show less
Alternatives
Epitope
AA 259-287, C-Term
(59), (43), (30), (24), (23), (21), (15), (13), (12), (6), (5), (4), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine), Zebrafish (Danio rerio)
(316), (145), (114), (8), (5), (4), (4), (3), (2), (2)
Host
Rabbit
(290), (39)
Clonality (Clone)
Polyclonal ()
Conjugate
This MAP2K4 antibody is un-conjugated
(12), (12), (11), (8), (8), (8), (5), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(212), (147), (113), (66), (45), (21), (17), (15), (14), (11), (4), (3), (2)
Pubmed 2 references available
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Quantity 400 μL
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Immunogen This Mouse Map2k4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 259-287 AA from the C-terminal region of mouse Map2k4.
Clone RB35403
Isotype Ig
Specificity This Mouse Map2k4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 258-287 amino acids from the C-terminal region of Mouse Map2k4.
Predicted Reactivity Xenopus laevis
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name Map2k4 (MAP2K4 Antibody Abstract)
Background Dual specificity kinase that activates the JUN kinases MAPK8 (JNK1) and MAPK9 (JNK2) as well as MAPK14 (p38) but not MAPK1 (ERK2) or MAPK3 (ERK1).
Synonyms: Dual specificity mitogen-activated protein kinase kinase 4,Map2k4,Jnkk1, Prkmk4, Sek1, Serk1
Research Area Ubiquitin-related antibodies, Signaling, Phospho-specific antibodies, Cell Signaling, Protein Modifications, Chromatin, Cell Structure
Pathways MAPK Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway
Application Notes WB = 1:1000, IHC (p) = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.48 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Supplier Images
Western Blotting (WB) image for anti-MAP2K4 antibody (Mitogen-Activated Protein Kinase Kinase 4) (AA 259-287) (ABIN658838) Mouse Map2k4 Antibody (C-term) western blot analysis in mouse NIH-3T3 cell line lysa...
Western Blotting (WB) image for anti-MAP2K4 antibody (Mitogen-Activated Protein Kinase Kinase 4) (AA 259-287) (ABIN658838) Mouse Map2k4 Antibody (C-term) western blot analysis in Y79 cell line lysates (35ug/...
Western Blotting (WB) image for anti-MAP2K4 antibody (Mitogen-Activated Protein Kinase Kinase 4) (AA 259-287) (ABIN658838) Mouse Map2k4 Antibody (C-term) western blot analysis in zebra fish brain tissue lysa...
Immunohistochemistry (IHC) image for anti-MAP2K4 antibody (Mitogen-Activated Protein Kinase Kinase 4) (AA 259-287) (ABIN658838) Mouse Map2k4 Antibody (C-term) (AP14920b)immunohistochemistry analysis in formalin fi...
Background publications Finegan, Tournier: "The mitogen-activated protein kinase kinase 4 has a pro-oncogenic role in skin cancer." in: Cancer research, Vol. 70, Issue 14, pp. 5797-806, 2010 (PubMed).

Ahn, Kurie: "MKK4/SEK1 is negatively regulated through a feedback loop involving the E3 ubiquitin ligase itch." in: The Journal of biological chemistry, Vol. 284, Issue 43, pp. 29399-404, 2009 (PubMed).

Catalog No. ABIN658838
$324.50
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