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Details for Product No. ABIN658838

Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4) (C-Term), (AA 259-287) antibody

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Antigen
Synonyms
JNKK, JNKK1, MAPKK4, MEK4, MKK4, PRKMK4, SAPKK-1, SAPKK1, SEK1, SERK1, SKK1, Sek1, Serk1, MKK4A-l, map2k4, zgc:136500, jnkk, mek4, mkk4, sek1, jnkk1, serk1, xmek2, mapkk4, prkmk4, 142758_at, CG9738, C ... show more
Epitope
»Alternatives C-Term, AA 259-287
Reactivity
»Alternatives Human, Mouse (Murine), Zebrafish (Danio rerio)
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 2 references available
Catalog no. ABIN658838
Quantity 400 ┬ÁL
Price
291.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen This Mouse Map2k4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 259-287 AA from the C-terminal region of mouse Map2k4.
Clone RB35403
Isotype Ig
Specificity This Mouse Map2k4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 258-287 amino acids from the C-terminal region of Mouse Map2k4.
Predicted Reactivity Xenopus laevis
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name Map2k4
Background Dual specificity kinase that activates the JUN kinases MAPK8 (JNK1) and MAPK9 (JNK2) as well as MAPK14 (p38) but not MAPK1 (ERK2) or MAPK3 (ERK1).
Synonyms: Dual specificity mitogen-activated protein kinase kinase 4,Map2k4,Jnkk1, Prkmk4, Sek1, Serk1
Research Area Ubiquitin-related antibodies, Signaling, Phospho-specific antibodies, Cell Signaling, Protein Modifications, Chromatin, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.48 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Background publications Ahn, Kurie: "MKK4/SEK1 is negatively regulated through a feedback loop involving the E3 ubiquitin ligase itch." in: The Journal of biological chemistry, Vol. 284, Issue 43, pp. 29399-404, 2009 (PubMed).

Finegan, Tournier: "The mitogen-activated protein kinase kinase 4 has a pro-oncogenic role in skin cancer." in: Cancer research, Vol. 70, Issue 14, pp. 5797-806, 2010 (PubMed).

Alternatives for antigen "Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4)", type "Antibodies"
Hosts (196), (25), (1)
Reactivities (220), (151), (144), (60), (52), (48), (36), (12), (1), (1)
Applications (122), (71), (71), (58), (50), (32), (12), (9), (6), (5), (3), (2), (2), (1)
Conjugates (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5)
Epitopes (51), (38), (34), (6), (4), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
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