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Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4) (C-Term) antibody

Antigen

Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4)
Synonyms
JNKK, MEK4, MKK4, SEK1, JNKK1, SERK1, MAPKK4, PRKMK4, Sek1, Serk1, map2k4a, MGC136500, zgc:136500, jnkk, mek4, mkk4, sek1, jnkk1, serk1, xmek2, mapkk4, prkmk4, 142758_at, CT27508, D-MKK4, DMKK4, JNKK2 ... show more
Binding Site
Alternatives

C-Term
Clonality Polyclonal
Host
Alternatives

Rabbit
Reactivity
Alternatives

Mouse (Murine)
Conjugate
Alternatives Un-conjugated
Application
Alternatives Western Blotting (WB), ELISA
2 references available
Certificates ISO 9001:2008
Catalog no. ABIN658838
Quantity 0.1 mg  (0.25 mg/ml)
Price 280.50 $   Plus shipping costs $45.00
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Additional Information
Application Details Publications Alternatives back to top

Alternative name Map2k4
Isotype Ig
Description Other names: Dual specificity mitogen-activated protein kinase kinase 4,Map2k4,Jnkk1, Prkmk4, Sek1, Serk1
Characteristics Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Specificity This Mouse Map2k4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 258-287 amino acids from the C-terminal region of Mouse Map2k4.
Comments

Background: Dual specificity kinase that activates the JUN kinases MAPK8 (JNK1) and MAPK9 (JNK2) as well as MAPK14 (p38) but not MAPK1 (ERK2) or MAPK3 (ERK1).
Synonyms JNKK, MEK4, MKK4, SEK1, JNKK1, SERK1, MAPKK4, PRKMK4, Sek1, Serk1, map2k4a, MGC136500, zgc:136500, jnkk, mek4, mkk4, sek1, jnkk1, serk1, xmek2, mapkk4, prkmk4, 142758_at, CT27508, D-MKK4, DMKK4, JNKK2, Mpk4, SEK1/MKK4, DmelCG9738, CG9738, CT38386, DmelCG12798, CG12798, DmelCR12798

Application Details
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Concentration 0.25 mg/ml
Purification Purified
Research Area Ubiquitin-related antibodies, Signaling, Phospho-specific antibodies, Cell Signaling, Protein Modifications, Chromatin, Cell Structure
Restrictions For Research Use only

Publications
Application Details Alternatives back to top

Product Ahn, Kurie: "MKK4/SEK1 is negatively regulated through a feedback loop involving the E3 ubiquitin ligase itch." in: The Journal of biological chemistry, Vol. 284, Issue 43, pp. 29399-404, 2009 (PubMed).

Finegan, Tournier: "The mitogen-activated protein kinase kinase 4 has a pro-oncogenic role in skin cancer." in: Cancer research, Vol. 70, Issue 14, pp. 5797-806, 2010 (PubMed).

Alternatives
Application Details Publications back to top

Alternatives for antigen "Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4)", type "Antibodies"
Hosts Rabbit (112), Mouse (13), Rat (1)
Reactivities Human (125), Rat (Rattus) (88), Mouse (Murine) (86), Dog (Canine) (26), Cow (Bovine) (23), Guinea Pig (5), Horse (Equine) (5), Pig (Porcine) (5)
Applications Western Blotting (WB) (60), Immunofluorescence (IF) (53), Immunohistochemistry (IHC) (43), ELISA (34), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (25), Immunocytochemistry (ICC) (9), Immunoprecipitation (IP) (5), Flow Cytometry (FACS) (3), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Dot Blot (DB) (1), Dot Blot (Dot) (1), Immunoelectron Microscopy (IEM) (1)
Conjugates Alexa Fluor 350 (5), Alexa Fluor 488 (5), Alexa Fluor 555 (5), Alexa Fluor 647 (5), PE,Cy5.5 (5), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy7 (1)
Epitopes pSer80 (16), pThr261 (13), pSer257 (5), Ser80 (4), pThr261,pSer257 (4), C-Term (2), Internal Region (2), Thr261 (2), pSer257, pThr261 (2), pSer47 (2), N-Term (1), Ser257 (1)