Indian Hedgehog antibody (IHH) (AA 51-80)

Details for Product anti-IHH Antibody No. ABIN658852, Supplier: Log in to see
Antigen
  • BDA1
  • HHG2
  • X-hh
  • Xbhh
  • bhh
  • bhh-a
  • IHH
  • ehh
  • zgc:113262
  • Indian hedgehog
  • indian hedgehog
  • Indian hedgehog homolog b
  • IHH
  • Ihh
  • ihh
  • ihhb
Alternatives
anti-Human Indian Hedgehog antibody for ELISA
Epitope
AA 51-80, N-Term
46
23
16
6
6
4
4
3
2
2
2
2
1
1
1
1
1
1
Reactivity
Human
146
72
35
2
2
2
1
1
1
1
1
1
1
1
1
Host
Rabbit
117
34
13
1
Clonality (Clone)
Polyclonal ()
Conjugate
This Indian Hedgehog antibody is un-conjugated
14
12
12
6
6
6
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
129
88
44
13
12
7
2
1
1
Options
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Immunogen This IHH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-80 AA from the N-terminal region of human IHH.
Clone RB35519
Isotype Ig
Specificity This IHH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50-80 amino acids from the N-terminal region of human IHH.
Predicted Reactivity Mouse (Murine)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name IHH (IHH Antibody Abstract)
Background This gene encodes a member of the hedgehog family of secreted signaling molecules. Hedgehog proteins are essential regulators of a variety of developmental processes including growth, patterning and morphogenesis. The encoded protein specifically plays a role in bone growth an differentiation. Mutations in this gene are the cause of brachydactyly type A1 which is characterized by shortening or malformation of the phalanges. Mutations in this gene are also the cause of acrocapitofemoral dysplasia.
Synonyms: Indian hedgehog protein,IHH,
Research Area Cell Signaling, Protein Modifications, Cell Structure, Metabolism
Pathways Hedgehog Signaling
Application Notes WB = 1:1000, IHC (p) = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Supplier Images
Western Blotting (WB) image for anti-Indian Hedgehog antibody (IHH) (AA 51-80) (ABIN658852) IHH Antibody (N-term) (ABIN658852) western blot analysis in HepG2 cell line lysates (...
Background publications Okada, Kamatani, Takahashi, Matsuda, Hosono, Ohmiya, Daigo, Yamamoto, Kubo, Nakamura, Kamatani: "A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci." in: Human molecular genetics, Vol. 19, Issue 11, pp. 2303-12, 2010 (PubMed).

Chuang, McMahon: "Vertebrate Hedgehog signalling modulated by induction of a Hedgehog-binding protein." in: Nature, Vol. 397, Issue 6720, pp. 617-21, 1999 (PubMed).