Indian Hedgehog (IHH) (N-Term), (AA 51-80) antibody

Details for Product No. ABIN658852
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Antigen
Synonyms BDA1, HHG2, X-hh, Xbhh, bhh, bhh-a, IHH, ehh, zgc:113262
Epitope
N-Term, AA 51-80
(22), (13), (8), (4), (4), (2), (2), (2), (1), (1), (1)
Reactivity
Human
(65), (39), (24), (12), (12), (1), (1), (1)
Host
Rabbit
(63), (8), (4), (1)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(7), (5), (5), (3), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Immunohistochemistry (IHC)
(60), (39), (22), (10), (10), (7), (2), (2), (2), (1)
Pubmed 2 references available
Quantity 400 μL
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Catalog No. ABIN658852
291.50 $
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Immunogen This IHH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-80 AA from the N-terminal region of human IHH.
Clone RB35519
Isotype Ig
Specificity This IHH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50-80 amino acids from the N-terminal region of human IHH.
Predicted Reactivity Mouse (Murine)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name IHH
Background This gene encodes a member of the hedgehog family of secreted signaling molecules. Hedgehog proteins are essential regulators of a variety of developmental processes including growth, patterning and morphogenesis. The encoded protein specifically plays a role in bone growth an differentiation. Mutations in this gene are the cause of brachydactyly type A1 which is characterized by shortening or malformation of the phalanges. Mutations in this gene are also the cause of acrocapitofemoral dysplasia.
Synonyms: Indian hedgehog protein,IHH,
Research Area Cell Signaling, Protein Modifications, Cell Structure, Metabolism
Application Notes WB = 1:1000, IHC = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Supplier Images
anti-Indian Hedgehog (IHH) (N-Term), (AA 51-80) antibody IHH Antibody (N-term) (ABIN658852) western blot analysis in HepG2 cell line lysates (35 µg/lane). This demonstrates the IHH antibody detected the IHH protein (arrow).
Background publications Chuang, McMahon: "Vertebrate Hedgehog signalling modulated by induction of a Hedgehog-binding protein." in: Nature, Vol. 397, Issue 6720, pp. 617-21, 1999 (PubMed).

Okada, Kamatani, Takahashi et al.: "A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci." in: Human molecular genetics, Vol. 19, Issue 11, pp. 2303-12, 2010 (PubMed).

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