You are viewing an incomplete version of our website. Please click to reload the website as full version.

Integrin beta 3 antibody (ITGB3) (Tyr785)

Details for Product anti-ITGB3 Antibody No. ABIN658966, Supplier: Log in to see
Antigen
  • BDPLT2
  • BDPLT16
  • CD61
  • GP3A
  • GPIIIA
  • GPIIIa
  • GT
  • INGRB3
  • INTB3
  • integrin
Epitope
Tyr785
46
42
31
19
13
9
8
7
7
7
5
4
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
527
218
184
20
20
19
15
11
8
8
5
5
5
4
3
3
3
2
2
1
1
Host
Mouse
330
222
61
32
9
1
Clonality
Monoclonal
Conjugate
This Integrin beta 3 antibody is un-conjugated
85
55
26
16
12
11
10
8
7
7
5
5
5
5
5
5
5
4
4
4
4
2
2
2
2
2
2
2
Application
Western Blotting (WB)
387
265
147
116
81
76
73
50
32
26
23
11
6
5
5
5
4
4
2
2
2
2
1
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Isotype IgG
Specificity The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purification Affinity purified
Alternative Name Integrin Beta-3 (ITGB3 Antibody Abstract)
Background The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling.
Synonyms: CD_antigen=CD61, Flags: Precursor, Platelet membrane glycoprotein IIIa, GPIIIa, Integrin beta-3
Molecular Weight 87058 DA
Gene ID 3690
UniProt P05106
Research Area Phospho-specific antibodies, Cell Signaling, Cell Structure, Protein Modifications
Application Notes The suggested dilution is: WB: 1:500-1:1000
Comment

Background: The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling.

Restrictions For Research Use only
Format Liquid
Concentration 1mg/ml
Buffer PBS, 0.02% sodium azide and 50% glycerol.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid freeze-thaw cycles.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Addad, Elalamy, Chakroun, Abderrazek, Dridi, Hamdi, Hassine, Ben-Farhat, Gerotziafas, Hatmi, Gamra: "Platelet glycoprotein IIIa (platelet antigen 1/platelet antigen 2) polymorphism and 1-year outcome in patients with stable coronary artery disease." in: Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, Vol. 21, Issue 7, pp. 674-8, 2010 (PubMed).

Motovska, Kvasnicka, Hajkova, Kala, Simek, Bobcikova, Petr, Bilkova, Poloczek, Miklik, Fischerova, Maly, Widimsky: "Platelet gene polymorphisms and risk of bleeding in patients undergoing elective coronary angiography: a genetic substudy of the PRAGUE-8 trial." in: Atherosclerosis, Vol. 212, Issue 2, pp. 548-52, 2010 (PubMed).

Romero, Friel, Velez Edwards, Kusanovic, Hassan, Mazaki-Tovi, Vaisbuch, Kim, Erez, Chaiworapongsa, Pearce, Bartlett, Salisbury, Anant, Vovis, Lee, Gomez, Behnke, Oyarzun, Tromp, Williams, Menon: "A genetic association study of maternal and fetal candidate genes that predispose to preterm prelabor rupture of membranes (PROM)." in: American journal of obstetrics and gynecology, Vol. 203, Issue 4, pp. 361.e1-361.e30, 2010 (PubMed).

Nie, Zhou, Fu, Wang, Ma: "The allele frequencies of HPA 1-16 determined by PCR-SSP in Chinese Cantonese donors." in: Transfusion medicine (Oxford, England), Vol. 20, Issue 6, pp. 376-82, 2010 (PubMed).

Jugessur, Shi, Gjessing, Lie, Wilcox, Weinberg, Christensen, Boyles, Daack-Hirsch, Nguyen, Christiansen, Lidral, Murray: "Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia." in: PLoS ONE, Vol. 5, Issue 7, pp. e11493, 2010 (PubMed).