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Details for Product No. ABIN658968

Integrin beta 3 (ITGB3) (pTyr785) antibody

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Antigen
Synonyms BDPLT16, BDPLT2, CD61, GP3A, GPIIIa, GT, INGRB3, integrin
Epitope
»Alternatives pTyr785
Reactivity
»Alternatives Human
Host
»Alternatives Mouse
Clonality Monoclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB)
Pubmed 5 references available
Catalog no. ABIN658968
Quantity 0.1 mg
Price
464.29 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Isotype IgG
Specificity The antibody was affinity-purified from rabbit antiserum using epitope-specific phosphopeptide column, and the antibody against non-phosphopeptide was removed using non-phosphopeptide column corresponding to the phosphorylation site.
Purification Affinity purified
Alternative Name Integrin Beta-3
Background The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling.
Synonyms: CD_antigen=CD61, Flags: Precursor, Platelet membrane glycoprotein IIIa, GPIIIa, Integrin beta-3
Molecular Weight 87058 DA
Gene ID 3690
UniProt P05106
Research Area Phospho-specific antibodies, Cell Signaling, Cell Structure, Protein Modifications
Application Notes The suggested dilution is: WB: 1:500~1:1000
Comment

Background: The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling.

Restrictions For Research Use only
Format Liquid
Concentration 1mg/ml
Buffer PBS, 0.02% sodium azide and 50% glycerol.
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Jugessur, Shi, Gjessing et al.: "Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia." in: PLoS ONE, Vol. 5, Issue 7, pp. e11493, 2010 (PubMed).

Nie, Zhou, Fu et al.: "The allele frequencies of HPA 1-16 determined by PCR-SSP in Chinese Cantonese donors." in: Transfusion medicine (Oxford, England), Vol. 20, Issue 6, pp. 376-82, 2010 (PubMed).

Romero, Friel, Velez Edwards et al.: "A genetic association study of maternal and fetal candidate genes that predispose to preterm prelabor rupture of membranes (PROM)." in: American journal of obstetrics and gynecology, Vol. 203, Issue 4, pp. 361.e1-361.e30, 2010 (PubMed).

Motovska, Kvasnicka, Hajkova et al.: "Platelet gene polymorphisms and risk of bleeding in patients undergoing elective coronary angiography: a genetic substudy of the PRAGUE-8 trial." in: Atherosclerosis, Vol. 212, Issue 2, pp. 548-52, 2010 (PubMed).

Addad, Elalamy, Chakroun et al.: "Platelet glycoprotein IIIa (platelet antigen 1/platelet antigen 2) polymorphism and 1-year outcome in patients with stable coronary artery disease." in: Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, Vol. 21, Issue 7, pp. 674-8, 2010 (PubMed).

Alternatives for antigen "Integrin beta 3 (ITGB3)", type "Antibodies"
Hosts (164), (159), (41), (2), (1)
Reactivities (301), (150), (81), (48), (45), (27), (26), (9), (8), (3), (2), (1), (1), (1), (1)
Applications (183), (158), (75), (57), (49), (42), (35), (30), (17), (14), (14), (4), (3), (2), (1)
Conjugates (54), (28), (22), (7), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (1), (1), (1), (1), (1)
Epitopes (35), (33), (13), (8), (4), (4), (3), (2), (2), (2), (1), (1), (1), (1), (1)
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