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BMP4 antibody (Bone Morphogenetic Protein 4)

Details for Product anti-BMP4 Antibody No. ABIN659071, Supplier: Log in to see
Antigen
  • bmp-4
  • zbmp-4
  • zgc:100779
  • XBMP-4
  • bmp2b
  • bmp2b1
  • bmp4
  • ofc11
  • xbmp4
  • zyme
  • BMP4
  • bmp-2
  • bmp2
  • bmp2-4
  • cb670
  • zbmp-2
  • zbmp2
  • BMP2B
  • BMP2B1
  • MCOPS6
  • OFC11
  • ZYME
  • Bmp-4
  • Bmp2b
  • Bmp2b-1
  • Bmp2b1
  • BOMPR4A
  • BMP-4
Reactivity
Human
141
47
47
15
12
9
8
7
3
3
1
1
1
1
1
1
1
1
1
Host
Mouse
164
37
9
1
Clonality (Clone)
Monoclonal ()
Conjugate
This BMP4 antibody is un-conjugated
19
16
6
3
2
2
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
134
97
55
30
16
11
11
8
4
4
3
1
1
1
1
Supplier
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Immunogen This BMP4 monoclonal antibody is generated from mouse immunized with BMP4 recombinant protein.
Clone 192CT7-2-6
Isotype IgM, kappa
Specificity This BMP4 monoclonal antibody is generated from mouse immunized with BMP4 recombinant protein.
Purification This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.
Alternative Name BMP4 (BMP4 Antibody Abstract)
Background The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein.
Synonyms: Bone morphogenetic protein 4,BMP4,BMP2B, DVR4
Molecular Weight 46555 DA
Gene ID 652
NCBI Accession NP_001193, NP_570911, NP_570912
UniProt P12644
Research Area Cell Signaling, Protein Modifications, Cell Cycle, Cell Structure
Application Notes WB = 1:100-500
Restrictions For Research Use only
Format Liquid
Concentration 1.2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-BMP4 antibody (Bone Morphogenetic Protein 4) (ABIN659071) BMP4 Antibody western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This de...
Background publications Nikopensius, Jagomägi, Krjutskov et al.: "Genetic variants in COL2A1, COL11A2, and IRF6 contribute risk to nonsyndromic cleft palate." in: Birth defects research. Part A, Clinical and molecular teratology, Vol. 88, Issue 9, pp. 748-56, 2010 (PubMed).

Kim, Lee, Jung et al.: "Genetic variants that affect length/height in infancy/early childhood in Vietnamese-Korean families." in: Journal of human genetics, Vol. 55, Issue 10, pp. 681-90, 2010 (PubMed).

Kupfer, Anderson, Hooker et al.: "Genetic heterogeneity in colorectal cancer associations between African and European americans." in: Gastroenterology, Vol. 139, Issue 5, pp. 1677-85, 1685.e1-8, 2010 (PubMed).

Jugessur, Shi, Gjessing et al.: "Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia." in: PLoS ONE, Vol. 5, Issue 7, pp. e11493, 2010 (PubMed).