|+1 404 474 4654|
|+1 888 205 9894 (TF)|
Unc-51 Like Kinase 2 (C. Elegans) (ULK2) antibody
|Synonyms||ULK2, MGC160050, Unc51.2, AU015340, mKIAA0623, A830085I22Rik|
Alternatives Western Blotting (WB), ELISA
|4 references available|
|Quantity||0.1 mg (0.25 mg/ml) (Variants)|
|Price||280.50 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 2 to 3 Business Days|
|UniProt||NP_055498.3, NP_001136082.1, Q8IYT8|
|Immunogen||This ULK2 monoclonal antibody is generated from mouse immunized with ULK2 recombinant protein.|
|Isotype||IgM, kappa chain|
|Description||Other names: 218CT21.2.6|
|Specificity||This ULK2 monoclonal antibody is generated from mouse immunized with ULK2 recombinant protein.|
|Molecular Weight||112694 DA|
Background: This gene encodes a protein that is similar to a serine/threonine kinase in C. elegans which is involved in axonal elongation. The structure of this protein is similar to the C. elegans protein in that both proteins have an N-terminal kinase domain, a central proline/serine rich (PS) domain, and a C-terminal (C) domain. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq].
|Application Notes||The suggested dilution is: ELISA~~1:1000 Western blotting~~ 1:20~100|
|Buffer||Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles|
|Research Area||Cell Structure, Signaling, Protein Modifications, Cell Signaling, Chromatin, Phospho-specific antibodies|
|Restrictions||For Research Use only|
Yan, Kuroyanagi, Tomemori et al.: "Mouse ULK2, a novel member of the UNC-51-like protein kinases: unique features of functional domains." in: Oncogene, Vol. 18, Issue 43, pp. 5850-9, 1999 (PubMed).
Tomoda, Kim, Zhan et al.: "Role of Unc51.1 and its binding partners in CNS axon outgrowth." in: Genes & development, Vol. 18, Issue 5, pp. 541-58, 2004 (PubMed).
Stelzl, Worm, Lalowski et al.: "A human protein-protein interaction network: a resource for annotating the proteome." in: Cell, Vol. 122, Issue 6, pp. 957-68, 2005 (PubMed).
Watkins, Rukazenkov: "Response to 'Clinical outcomes in NSCLC patients with EGFR mutations: pooled analysis' (Paz-Ares et al., J Cell Mol Med. 2010; 14: 51-69)." in: Journal of cellular and molecular medicine, Vol. 14, Issue 11, pp. 2693-4, 2010 (PubMed).
|Hosts||Rabbit (6), Mouse (3)|
|Applications||Western Blotting (WB) (9), ELISA (7), Immunohistochemistry (IHC) (2), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (1)|
|Epitopes||C-Term (3), N-Term (2), Internal Region (1), Met10 (1)|