Unc-51 Like Kinase 2 (C. Elegans) (ULK2) antibody

Details for Product No. ABIN659090
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Synonyms Unc51.2, AU015340, mKIAA0623, A830085I22Rik, ATG1B, ULK2
(34), (4), (1), (1), (1)
(19), (18)
Clonality (Clone)
Monoclonal ()
Western Blotting (WB)
(34), (14), (6), (4), (3), (3), (1)
Pubmed 4 references available
Catalog no. ABIN659090
Quantity 400 µL
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Immunogen This ULK2 monoclonal antibody is generated from mouse immunized with ULK2 recombinant protein.
Clone 218CT21-2-6
Isotype IgM, kappa
Specificity This ULK2 monoclonal antibody is generated from mouse immunized with ULK2 recombinant protein.
Purification This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.
Alternative Name ULK2
Background This gene encodes a protein that is similar to a serine/threonine kinase in C. elegans which is involved in axonal elongation. The structure of this protein is similar to the C. elegans protein in that both proteins have an N-terminal kinase domain, a central proline/serine rich (PS) domain, and a C-terminal (C) domain. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq].
Synonyms: 218CT21.2.6
Molecular Weight 112694 DA
Gene ID 9706
UniProt NP_055498.3, NP_001136082.1, Q8IYT8
Research Area Cell Structure, Signaling, Protein Modifications, Cell Signaling, Chromatin, Phospho-specific antibodies
Application Notes WB = 1:100
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Unc-51 Like Kinase 2 (C. Elegans) (ULK2) antibody ULK2 antibody western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the ULK2 antibody detected the ULK2 protein (arrow).
Background publications Yan, Kuroyanagi, Tomemori et al.: "Mouse ULK2, a novel member of the UNC-51-like protein kinases: unique features of functional domains." in: Oncogene, Vol. 18, Issue 43, pp. 5850-9, 1999 (PubMed).

Tomoda, Kim, Zhan et al.: "Role of Unc51.1 and its binding partners in CNS axon outgrowth." in: Genes & development, Vol. 18, Issue 5, pp. 541-58, 2004 (PubMed).

Stelzl, Worm, Lalowski et al.: "A human protein-protein interaction network: a resource for annotating the proteome...." in: Cell, Vol. 122, Issue 6, pp. 957-68, 2005 (PubMed).

Watkins, Rukazenkov: "Response to 'Clinical outcomes in NSCLC patients with EGFR mutations: pooled analysis'
(Paz-Ares et al., J Cell Mol Med. 2010; 14: 51-69)." in: Journal of cellular and molecular medicine, Vol. 14, Issue 11, pp. 2693-4, 2010 (PubMed).

Hosts (19), (18)
Reactivities (34), (4), (1), (1), (1)
Applications (34), (14), (6), (4), (3), (3), (1)
Epitopes (12), (4), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
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