ULK2 antibody (Unc-51 Like Kinase 2 (C. Elegans))

Details for Product anti-ULK2 Antibody No. ABIN659090, Supplier: Log in to see
Antigen
  • ULK2
  • ATG1B
  • Unc51.2
  • A830085I22Rik
  • AU015340
  • mKIAA0623
  • unc-51-like kinase 2 (C. elegans)
  • unc-51 like autophagy activating kinase 2
  • unc-51 like kinase 2
  • ULK2
  • Ulk2
  • ulk2
Alternatives
anti-Human ULK2 antibody for Dot Blot
Reactivity
Human
138
28
25
Host
Mouse
105
35
Clonality (Clone)
Monoclonal ()
Conjugate
This ULK2 antibody is un-conjugated
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8
8
8
8
8
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
102
84
29
28
24
17
12
4
2
1
1
1
Options
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Immunogen This ULK2 monoclonal antibody is generated from mouse immunized with ULK2 recombinant protein.
Clone 218CT21-2-6
Isotype IgM, kappa
Specificity This ULK2 monoclonal antibody is generated from mouse immunized with ULK2 recombinant protein.
Purification This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.
Alternative Name ULK2 (ULK2 Antibody Abstract)
Background This gene encodes a protein that is similar to a serine/threonine kinase in C. elegans which is involved in axonal elongation. The structure of this protein is similar to the C. elegans protein in that both proteins have an N-terminal kinase domain, a central proline/serine rich (PS) domain, and a C-terminal (C) domain. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq].
Synonyms: 218CT21.2.6
Molecular Weight 112694 DA
Gene ID 9706
NCBI Accession NP_001136082, NP_055498
UniProt Q8IYT8
Research Area Cell Structure, Signaling, Protein Modifications, Cell Signaling, Chromatin, Phospho-specific antibodies
Pathways Regulation of Cell Size
Application Notes WB = 1:100
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-ULK2 antibody (Unc-51 Like Kinase 2 (C. Elegans)) (ABIN659090) ULK2 antibody western blot analysis in U251 cell line lysates (35ug/lane).This demo...
Background publications Watkins, Rukazenkov: "Response to 'Clinical outcomes in NSCLC patients with EGFR mutations: pooled analysis'
(Paz-Ares et al., J Cell Mol Med. 2010; 14: 51-69)." in: Journal of cellular and molecular medicine, Vol. 14, Issue 11, pp. 2693-4, 2010 (PubMed).

Stelzl, Worm, Lalowski, Haenig, Brembeck, Goehler, Stroedicke, Zenkner, Schoenherr, Koeppen, Timm, Mintzlaff, Abraham, Bock, Kietzmann, Goedde, Toksöz, Droege, Krobitsch, Korn, Birchmeier, Lehrach et al.: "A human protein-protein interaction network: a resource for annotating the proteome. ..." in: Cell, Vol. 122, Issue 6, pp. 957-68, 2005 (PubMed).

Tomoda, Kim, Zhan, Hatten: "Role of Unc51.1 and its binding partners in CNS axon outgrowth." in: Genes & development, Vol. 18, Issue 5, pp. 541-58, 2004 (PubMed).

Yan, Kuroyanagi, Tomemori, Okazaki, Asato, Matsuda, Suzuki, Ohshima, Mitani, Masuho, Shirasawa, Muramatsu: "Mouse ULK2, a novel member of the UNC-51-like protein kinases: unique features of functional domains." in: Oncogene, Vol. 18, Issue 43, pp. 5850-9, 1999 (PubMed).