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TGFB2 antibody (Transforming Growth Factor, beta 2)

Details for Product anti-TGFB2 Antibody No. ABIN659105, Supplier: Log in to see
Antigen
  • BB105277
  • LDS4
  • MGF
  • TGF-B2
  • Tgf-beta2
  • tgf-beta2
  • TGF-beta 2
  • TGF-beta2
  • Tgfb-2
  • TGFB2
  • tgfb2-A
  • TGFbeta2
  • Tgfbr2T
Reactivity
Human
131
38
35
6
4
3
2
2
1
1
Host
Mouse
119
25
1
Clonality (Clone)
Monoclonal ()
Conjugate
This TGFB2 antibody is un-conjugated
8
8
7
1
1
1
Application
Western Blotting (WB)
93
63
46
23
13
6
5
2
1
1
Supplier
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Immunogen This TGFB2 monoclonal antibody is generated from mouse immunized with TGFB2 recombinant protein.
Clone 220ct16-4-3-1
Isotype IgG1, kappa
Specificity This TGFB2 monoclonal antibody is generated from mouse immunized with TGFB2 recombinant protein.
Purification Ascites
Alternative Name TGFB2 (TGFB2 Antibody Abstract)
Background This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types by transducing their signal through combinations of transmembrane type I and type II receptors (TGFBR1 and TGFBR2) and their downstream effectors, the SMAD proteins. Disruption of the TGFB/SMAD pathway has been implicated in a variety of human cancers. The encoded protein is secreted and has suppressive effects of interleukin-2 dependent T-cell growth. Translocation t(1,7)(q41,p21) between this gene and HDAC9 is associated with Peters' anomaly, a congenital defect of the anterior chamber of the eye. The knockout mice lacking this gene show perinatal mortality and a wide range of developmental, including cardiac, defects. Alternatively spliced transcript variants encoding different isoforms have been identified.
Synonyms: 220ct16.4.3.1
Molecular Weight 47748 DA
Gene ID 7042
NCBI Accession NP_003229, NP_001129071
UniProt P61812
Research Area Cell Structure, Signaling, Protein Modifications, Cell Cycle, Cell Signaling, Chromatin
Application Notes WB = 1:500-16000
Restrictions For Research Use only
Format Liquid
Buffer Crude ascites with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid freeze-thaw cycles.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-TGFB2 antibody (Transforming Growth Factor, beta 2) (ABIN659105) TGFB2 antibody western blot analysis in A549 cell line lysates (35ug/lane).This dem...
Background publications Jugessur, Shi, Gjessing, Lie, Wilcox, Weinberg, Christensen, Boyles, Daack-Hirsch, Nguyen, Christiansen, Lidral, Murray: "Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia." in: PLoS ONE, Vol. 5, Issue 7, pp. e11493, 2010 (PubMed).

Sambo, Trovoada, Benchimol, Quinhentos, Gonçalves, Velosa, Marques, Sepúlveda, Clark, Mustafa, Wagner, Coutinho, Penha-Gonçalves: "Transforming growth factor beta 2 and heme oxygenase 1 genes are risk factors for the cerebral malaria syndrome in Angolan children." in: PLoS ONE, Vol. 5, Issue 6, pp. e11141, 2010 (PubMed).