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Eukaryotic Translation Initiation Factor 4E Family Member 2 (EIF4E2) antibody

Antigen

Eukaryotic Translation Initiation Factor 4E Family Member 2 (EIF4E2)
Synonyms EIF4E2, MGC152103, eif4e2, MGC158544, id:ibd1007, zgc:158544, MGC115622, DKFZp459H223
Clonality Monoclonal
Host
Alternatives

Mouse
Reactivity
Alternatives

Human
Application
Alternatives Western Blotting (WB), ELISA
4 references available
Certificates ISO 9001:2008
Catalog no. ABIN659115
Quantity 0.1 ml  (Crude ascites)  (Variants)
Price 280.50 $   Plus shipping costs $45.00
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Additional Information
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Alternative name EIF4E2
Gene ID 9470
UniProt NP_004837.1, O60573
Immunogen This EIF4E2 monoclonal antibody is generated from mouse immunized with EIF4E2 recombinant protein.
Format Ascites
Isotype IgG1 kappa
Description Other names: 225CT3.1.3
Characteristics Synthetic peptide
Specificity This EIF4E2 monoclonal antibody is generated from mouse immunized with EIF4E2 recombinant protein.
Molecular Weight 28362 DA
Comments

Background: EIF4E2 recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.

Application Details
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Application Notes The suggested dilution is: ELISA~~1:1000 Western blotting~~ 1:50~1600
Concentration Crude ascites
Buffer Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
Storage Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles
Research Area Cell Structure, Signaling, Protein Modifications, Chromatin, Translation Factors
Restrictions For Research Use only

Publications
Application Details Alternatives Variants back to top

Product Rosettani, Knapp, Vismara et al.: "Structures of the human eIF4E homologous protein, h4EHP, in its m7GTP-bound and unliganded forms." in: Journal of molecular biology, Vol. 368, Issue 3, pp. 691-705, 2007 (PubMed).

Zuberek, Kubacka, Jablonowska et al.: "Weak binding affinity of human 4EHP for mRNA cap analogs." in: RNA (New York, N.Y.), Vol. 13, Issue 5, pp. 691-7, 2007 (PubMed).

Venkatesan, Rual, Vazquez et al.: "An empirical framework for binary interactome mapping." in: Nature methods, Vol. 6, Issue 1, pp. 83-90, 2008 (PubMed).

Watkins, Rukazenkov: "Response to 'Clinical outcomes in NSCLC patients with EGFR mutations: pooled analysis'
(Paz-Ares et al., J Cell Mol Med. 2010; 14: 51-69)." in: Journal of cellular and molecular medicine, Vol. 14, Issue 11, pp. 2693-4, 2010 (PubMed).

Alternatives
Application Details Publications Variants back to top

Alternatives for antigen "Eukaryotic Translation Initiation Factor 4E Family Member 2 (EIF4E2)", type "Antibodies"
Hosts Rabbit (19), Mouse (9)
Reactivities Human (27), Mouse (Murine) (4), Rat (Rattus) (4), Cow (Bovine) (2), Dog (Canine) (2), Cat (Feline) (1), Chicken (1), Monkey (1), Pig (Porcine) (1)
Applications Western Blotting (WB) (28), ELISA (13), Immunohistochemistry (IHC) (11), Immunofluorescence (IF) (5), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (4), Flow Cytometry (FACS) (2), Immunoprecipitation (IP) (1)
Epitopes N-Term (8), Center (1)