Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) antibody

Details for Product No. ABIN659184
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Antigen
Synonyms
4E-BP1, 4EBP1, BP-1, PHAS-I, 4e-bp1, AA959816, 153432_at, 43-BP, 4E-BP, 4EBP, 4e-bp, 4eBP, 4ebp, BcDNA.HL08053, BcDNA:HL08053, CG8846, CT8705, Dm 4E-BP, Dmel\\CG8846, Phas1, Thor/EIF4EBP, anon-WO01727 ... show more
4E-BP1, 4EBP1, BP-1, PHAS-I, 4e-bp1, AA959816, 153432_at, 43-BP, 4E-BP, 4EBP, 4e-bp, 4eBP, 4ebp, BcDNA.HL08053, BcDNA:HL08053, CG8846, CT8705, Dm 4E-BP, Dmel\\CG8846, Phas1, Thor/EIF4EBP, anon-WO0172774.158, d4E-BP, d4E-BP1, d4EBP, d4e-bp, d4eBP, dthor, eIF4E-BP, l(2)06270, l(2)k07736, l(2)k13517, pp20, thor, EIF4EBP1, fc04h09, wu:fc04h09, zgc:64137 show less
Reactivity
Human
(325), (240), (186), (60), (60), (37), (24)
Host
Mouse
(322), (40), (21)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(20), (15), (7), (7), (7), (7), (7), (7), (7), (7), (7), (6)
Application
Western Blotting (WB)
(264), (151), (145), (79), (69), (30), (21), (16), (7), (6), (6), (2), (1), (1)
Pubmed 2 references available
Catalog no. ABIN659184
Quantity 0.1 mL
Price
291.50 $   Plus shipping costs $45.00
Options
Shipping to United States (Change)
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  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen This EIF4EBP1 monoclonal antibody is generated from mouse immunized with EIF4EBP1 recombinant protein.
Clone 319CT22-8-2
Isotype IgG1
Specificity This EIF4EBP1 monoclonal antibody is generated from mouse immunized with EIF4EBP1 recombinant protein.
Purification Ascites
Alternative Name EIF4EBP1
Background This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq].
Synonyms: Eukaryotic translation initiation factor 4E-binding protein 1,EIF4EBP1,
Molecular Weight 12580 DA
Gene ID 1978
UniProt NP_004086.1, Q13541
Research Area Translation Factors, Signaling, Phospho-specific antibodies, Protein Modifications, Cell Structure
Application Notes WB = 1:500-8000
Restrictions For Research Use only
Format Liquid
Buffer Crude ascites with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment EIF4EBP1 Antibody can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
anti-Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) antibody EIF4EBP1 Antibody western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the EIF4EBP1 antibody detected the EIF4EBP1 protein (arrow).
Background publications Aoyagi, Gaspar, Shenk: "Human cytomegalovirus UL69 protein facilitates translation by associating with the mRNA cap-binding complex and excluding 4EBP1." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 6, pp. 2640-5, 2010 (PubMed).

She, Halilovic, Ye et al.: "4E-BP1 is a key effector of the oncogenic activation of the AKT and ERK signaling pathways that integrates their function in tumors." in: Cancer cell, Vol. 18, Issue 1, pp. 39-51, 2010 (PubMed).

Hosts (322), (40), (21)
Reactivities (325), (240), (186), (60), (60), (37), (24)
Applications (264), (151), (145), (79), (69), (30), (21), (16), (7), (6), (6), (2), (1), (1)
Conjugates (20), (15), (7), (7), (7), (7), (7), (7), (7), (7), (7), (6)
Epitopes (38), (25), (24), (20), (18), (17), (17), (14), (13), (12), (11), (8), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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