Add to Basket Bulk discount
Order hotline:
+1 404 474 4654
+1 888 205 9894 (TF)

Chemokine (C-C Motif) Ligand 2 (CCL2) antibody

Antigen

Chemokine (C-C Motif) Ligand 2 (CCL2)
Synonyms HC11, MCAF, MCP1, MCP-1, SCYA2, GDCF-2, SMC-CF, HSMCR30, MGC9434, JE, Scya2, Sigje, AI323594, CCL2, DKFZp469C111
Clonality Monoclonal
Host
Alternatives

Mouse
Reactivity
Alternatives

Human
Conjugate
Alternatives Un-conjugated
Application
Alternatives Western Blotting (WB), ELISA
3 references available
Certificates ISO 9001:2008
Catalog no. ABIN659213
Quantity 0.1mg
Price 330.00 $   Plus shipping costs $45.00
Bulk discount
Shipping to
Availability Will be delivered in 2 to 3 Business Days

Additional Information
Application Details Publications Alternatives back to top

Alternative name MCP-1
Gene ID 6347
UniProt NP_002973.1, P13500
Immunogen Purified recombinant fragment of human MCP-1 expressed in E. Coli.
Isotype IgG1 kappa
Description Other names: MCP1
Characteristics Mouse Monoclonal antibody to MCP-1
Specificity Purified recombinant fragment of human MCP-1 expressed in E. Coli.
Molecular Weight 11025 DA
Comments

Background: Monocyte chemoattractant protein-1 (MCP-1) is a member of the chemokine-beta family of cytokines. The protein is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. It may play a inprotant role in the initiation and/or progression of pulmonary hypertension (PH). Blockade of a systemic MCP-1 signal pathway in vivo may prevent PH.

Application Details
Publications Alternatives back to top

Application Notes The suggested dilution is: ELISA: ~~ 1:10000. Western Bloting: ~~ 1:500 - 2000.
Buffer Purified recombinant fragment of human MCP-1 expressed in E. Coli.
Storage MCP-1 Antibody can be stored at 4?, for long term storage, store at -20?.
Research Area Cell Structure
Restrictions For Research Use only

Publications
Application Details Alternatives back to top

Product Yoshimura, Leonard: "Human monocyte chemoattractant protein-1 (MCP-1)." in: Advances in experimental medicine and biology, Vol. 305, pp. 47-56, 1992 (PubMed).

Rollins, Morton, Ledbetter et al.: "Assignment of the human small inducible cytokine A2 gene, SCYA2 (encoding JE or MCP-1), to 17q11.2-12: evolutionary relatedness of cytokines clustered at the same locus." in: Genomics, Vol. 10, Issue 2, pp. 489-92, 1991 (PubMed).

Yoshimura, Yuhki, Moore et al.: "Human monocyte chemoattractant protein-1 (MCP-1). Full-length cDNA cloning, expression in mitogen-stimulated blood mononuclear leukocytes, and sequence similarity to mouse competence gene JE." in: FEBS letters, Vol. 244, Issue 2, pp. 487-93, 1989 (PubMed).

Alternatives
Application Details Publications back to top

Alternatives for antigen "Chemokine (C-C Motif) Ligand 2 (CCL2)", type "Antibodies"
Hosts Rabbit (128), Mouse (58), Hamster (11), Guinea Pig (6), Rat (5), Sheep (2)
Reactivities Human (118), Mouse (Murine) (79), Rat (Rattus) (63), Cow (Bovine) (23), Dog (Canine) (23), Pig (Porcine) (22), Horse (Equine) (18), Rabbit (6), Cat (Feline) (3), Orang-Utan (3), Rhesus Monkey (3), Monkey (2)
Applications Western Blotting (WB) (141), ELISA (130), Immunohistochemistry (IHC) (41), Immunofluorescence (IF) (37), Neutralization (Neut) (24), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (23), Flow Cytometry (FACS) (16), Functional Studies (Func) (14), Immunoprecipitation (IP) (10), Immunocytochemistry (ICC) (9), Immunohistochemistry (Fixed) (IHC (fx)) (8), Immunoassay (IA) (7), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (6), Immunohistochemistry (Frozen Sections) (IHC (fro)) (3), Blocking Antibody (Inhibition) (2), Blocking Antibody (Inhibition) (2), Dot Blot (Dot) (2), Fluorescence Microscopy (FM) (2), Immunoelectron Microscopy (IEM) (2), ELISA (Detection) (1)
Conjugates Biotin (25), FITC (12), HRP (6), PE (5), APC (2), Alexa Fluor 350 (2), Alexa Fluor 488 (2), Alexa Fluor 555 (2), Alexa Fluor 647 (2), Cy3 (2), Cy5 (2), Cy5.5 (2), Cy7 (2), Gold (2), PE,Cy3 (2), PE,Cy5 (2), PE,Cy5.5 (2), PE,Cy7 (2)
Epitopes C-Term (4), AA 1-73 (3), AA 102-130 (3), AA 451-560 (1), Internal Region (1), N-Term,AA 24-36 (1)