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V-Yes-1 Yamaguchi Sarcoma Viral Oncogene Homolog 1 (YES1) antibody

Antigen

V-Yes-1 Yamaguchi Sarcoma Viral Oncogene Homolog 1 (YES1)

Synonyms Yes, c-yes, HsT441, P61-YES, yes, YES1, hst441, p61-yes, MGC89200
Clonality Monoclonal
Host
Alternatives

Mouse

Reactivity
Alternatives

Human

Conjugate
Alternatives Un-conjugated
Application
Alternatives Western Blotting (WB), ELISA
3 references available
Certificates ISO 9001:2008
Catalog no. ABIN659362
Quantity 0.1ml
Price 423.50 $   Plus shipping costs $45.00
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Additional Information

Alternative name YES1
Gene ID 7525
UniProt NP_005424.1, P07947
Immunogen Purified recombinant fragment of YES(aa10-193) expressed in E. Coli.
Isotype IgG1
Description Other names: Yes, c-yes, HsT441, P61-YES, YES1
Characteristics Mouse Monoclonal antibody to YES1
Specificity Purified recombinant fragment of YES(aa10-193) expressed in E. Coli.
Molecular Weight 60801 DA
Comments

Background: YES1, v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1. This gene is the cellular homolog of the Yamaguchi sarcoma virus oncogene. The encoded protein has tyrosine kinase activity and belongs to the src family of proteins. This gene lies in close proximity to thymidylate synthase gene on chromosome 18, and a corresponding pseudogene has been found on chromosome 22.

Application Details

Application Notes The suggested dilution is: ELISA: ~~ 1:10000. Western Bloting: ~~ 1:500 - 2000.
Buffer Purified recombinant fragment of YES(aa10-193) expressed in E. Coli.
Storage YES1 Antibody can be stored at 4?, for long term storage, store at -20?.
Research Area Ubiquitin-related antibodies, Phospho-specific antibodies, Cell Signaling, Chromatin, Signaling, Cell Structure
Restrictions For Research Use only

Publications

Product Reinehr, Becker, Höngen et al.: "The Src family kinase Yes triggers hyperosmotic activation of the epidermal growth factor receptor and CD95." in: The Journal of biological chemistry, Vol. 279, Issue 23, pp. 23977-87, 2004 (PubMed).

Annerén, Cowan, Melton: "The Src family of tyrosine kinases is important for embryonic stem cell self-renewal." in: The Journal of biological chemistry, Vol. 279, Issue 30, pp. 31590-8, 2004 (PubMed).

Rush, Moritz, Lee et al.: "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells." in: Nature biotechnology, Vol. 23, Issue 1, pp. 94-101, 2005 (PubMed).

Alternatives

Alternatives for antigen "V-Yes-1 Yamaguchi Sarcoma Viral Oncogene Homolog 1 (YES1)", type "Antibodies"
Hosts Rabbit (41), Mouse (8), Sheep (2)
Reactivities Human (49), Mouse (Murine) (33), Rat (Rattus) (32), Dog (Canine) (31), Chicken (30), Cow (Bovine) (30), Pig (Porcine) (29), Guinea Pig (24), Cat (Feline) (1)
Applications Immunofluorescence (IF) (29), Western Blotting (WB) (25), ELISA (21), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (8), Immunohistochemistry (IHC) (4), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunoprecipitation (IP) (3), Immunocytochemistry (ICC) (1), Immunoelectron Microscopy (IEM) (1)
Conjugates Alexa Fluor 350 (3), Alexa Fluor 488 (3), Alexa Fluor 555 (3), Alexa Fluor 647 (3), PE,Cy5.5 (3), Alexa Flour 488 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy7 (1)
Epitopes N-Term (5), pTyr527 (5), pTyr537 (5), AA 1-252 (1), AA 10-193 (1), AA 3-19 (1), AA 731-909 (1), pThr232 (1)