Fibulin 5 (FBLN5) antibody
| Antigen |
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| Synonyms |
EVEC, UP50, ARMD3, DANCE, FIBL-5, FLJ90059, A55, zgc:103575, FBLN5, MGC128763, MGC108414, Fibulin-5, DKFZp469K0327 |
| Clonality |
Monoclonal |
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Host
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Reactivity
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Conjugate
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Biotin (3), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
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Application
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 Alternatives Western Blotting (WB), Immunohistochemistry (IHC), ELISA
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| Catalog no. |
ABIN659371 |
| Quantity |
0.1ml (Variants) |
| Price |
423.50 $ Plus shipping costs $45.00
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Bulk discount
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| Shipping to |
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| Availability |
Will be delivered in 2 to 3 Business Days |
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Alternative name
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FBLN5
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Gene ID
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10516
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UniProt
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NP_006320.2, Q9UBX5
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Immunogen
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Purified recombinant fragment of FBLN5(aa242-448) expressed in E. Coli.
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Isotype
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IgG1
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Description
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Other names: EVEC, UP50, ARMD3, DANCE
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Characteristics
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Mouse Monoclonal Antibody to FBLN5
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Specificity
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Purified recombinant fragment of FBLN5(aa242-448) expressed in E. Coli.
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Molecular Weight
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50180 DA
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Comments
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Background: FBLN5: fibulin 5. The protein is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling.
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Application Notes
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The suggested dilution is: ELISA: ~~ 1:10000. Western Bloting: ~~ 1:500 - 2000. Immunohistochemistry: ~~ 1:200 - 1000.
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Buffer
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Purified recombinant fragment of FBLN5(aa242-448) expressed in E. Coli.
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Storage
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FBLN5 Antibody can be stored at 4?, for long term storage, store at -20?.
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Research Area
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Cell Signaling, Cell Structure
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Restrictions
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For Research Use only
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Product
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Markova, Zou, Ringpfeil et al.: "Genetic heterogeneity of cutis laxa: a heterozygous tandem duplication within the fibulin-5 (FBLN5) gene." in: American journal of human genetics, Vol. 72, Issue 4, pp. 998-1004, 2003 (PubMed).
Clark, Gurney, Abaya et al.: "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." in: Genome research, Vol. 13, Issue 10, pp. 2265-70, 2003 (PubMed).
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Alternatives for antigen "Fibulin 5 (FBLN5)", type "Antibodies"
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Hosts
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Rabbit (36), Mouse (24), Goat (4)
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Reactivities
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Human (62), Mouse (Murine) (32), Rat (Rattus) (28), Cow (Bovine) (23), Pig (Porcine) (22), Dog (Canine) (20), Chicken (19), Horse (Equine) (18), Rabbit (4), Cat (Feline) (1)
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Applications
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Western Blotting (WB) (49), ELISA (47), Immunohistochemistry (IHC) (26), Immunofluorescence (IF) (20), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (7), Immunoprecipitation (IP) (6), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (Fixed) (IHC (fx)) (1)
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Conjugates
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Biotin (3), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
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Epitopes
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C-Term (20), Internal Region (2), AA 242-448 (1), C-Term,AA 392-421 (1)
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