Apolipoprotein O (APOO) antibody

Details for Product No. ABIN659469
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Antigen
Synonyms FAM121B, 0610008C08Rik, 1110019O03Rik, RGD1565289, MGC79016, MGC140415, my025, fam121b, fp74f12, wu:fp74f12, zgc:123314
Reactivity
Human
(28), (19), (13), (13), (12), (12), (12)
Host
Mouse
(22), (8)
Clonality
Monoclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(21), (11), (10), (8), (6), (2), (2)
Pubmed 2 references available
Catalog no. ABIN659469
Quantity 0.1 mg
Price
357.50 $   Plus shipping costs $45.00
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Immunogen Purified recombinant fragment of ApoO expressed in E. Coli.
Isotype IgG1
Specificity Purified recombinant fragment of ApoO expressed in E. Coli.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name ApoO
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 22285 DA
Gene ID 12406
UniProt Q9BUR5, NP_077027.1
Research Area Cell Signaling, Cell Structure
Application Notes Western Bloting: = 1:500 - 2000.
Comment

Background: ApoO: apolipoprotein O, also known as MYO25, FAM121B, MGC4825. Entrez Protein NP_077027. It is a chrondroitin-sulfate chain containing member of the apolipoprotein family and is an original glycoprotein up-regulated by diabetes in human Heart. Promotes cholesterol efflux from macrophage cells. Detected in HDL, LDL and VLDL. Secreted by a microsomal triglyceride transfer protein (MTTP)-dependent mechanism, probably as a VLDL-associated protein that is subsequently transferred to HDL. May be involved in myocardium-protective mechanisms against lipid accumulation.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Clark, Gurney, Abaya et al.: "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment...." in: Genome research, Vol. 13, Issue 10, pp. 2265-70, 2003 (PubMed).

Lamant, Smih, Harmancey et al.: "ApoO, a novel apolipoprotein, is an original glycoprotein up-regulated by diabetes in human heart." in: The Journal of biological chemistry, Vol. 281, Issue 47, pp. 36289-302, 2006 (PubMed).

Hosts (22), (8)
Reactivities (28), (19), (13), (13), (12), (12), (12)
Applications (21), (11), (10), (8), (6), (2), (2)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (4), (2), (2), (1)
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