Neurogenin 3 (NEUROG3) antibody

Details for Product No. ABIN659521
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Antigen
Synonyms NEUROG3, ngn3, atoh5, ngn-3, bhlha7, math4b, neurog3, Ngn3, Atoh5, Math4B, NGN-3, bHLHa7, Relax, atoh4, ngn2, ngn3a
Reactivity
Human
(73), (23), (14), (13), (13), (3), (1)
Host
Mouse
(53), (26), (1)
Clonality
Monoclonal
Conjugate
Un-conjugated
(3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(60), (39), (21), (10), (7), (7), (6), (4), (1), (1)
Pubmed 2 references available
Quantity 0.1 mL
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Catalog No. ABIN659521
330.00 $
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Immunogen Purified recombinant fragment of human NGN3 expressed in E. Coli.
Isotype IgG1
Specificity Purified recombinant fragment of human NGN3 expressed in E. Coli.
Alternative Name Neurogenin-3
Background Beta-actin (PS1TP5-binding protein 1), also known as ACTB, PS1TP5BP1. Entrez Protein NP_001092. It is one of six different actin proteins. Actin, a ubiquitous eukaryotic protein, is the major component of the cytoskeleton.Actins are highly conserved proteins that are involved in various types of cell motility, structure, and integrity. Actin is ubiquitously expressed in all eukaryotic cells. This actin is a major constituent of the contractile apparatus and one of the two nonmuscle cytoskeletal actins.
Synonyms: PS1TP5BP1, ACTB
Molecular Weight 23077 DA
Gene ID 60
NCBI Accession NP_066279
UniProt Q9Y4Z2
Research Area Translation Factors, Transcription Factors, Neurology, Cell Structure
Application Notes Western Bloting: = 1:500 - 2000.
Comment

Background: Neurogenin-3 (NEUROG3), also known as NGN3, it is expressed in endocrine progenitor cells and is required for endocrine cell development in the pancreas and intestine. It belongs to a family of basic helix-loop-helix transcription factors involved in the determination of neural precursor cells in the neuroectoderm.

Restrictions For Research Use only
Format Liquid
Storage 4 °C/-20 °C
Storage Comment beta-Actin Antibody can be stored at 4°C, for long term storage, store at -20°C.
Background publications Gradwohl, Dierich, LeMeur et al.: "neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 97, Issue 4, pp. 1607-11, 2000 (PubMed).

Heremans, Van De Casteele, int Veld et al.: "Recapitulation of embryonic neuroendocrine differentiation in adult human pancreatic duct cells expressing neurogenin 3." in: The Journal of cell biology, Vol. 159, Issue 2, pp. 303-12, 2002 (PubMed).

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