|+1 404 474 4654|
|+1 888 205 9894 (TF)|
Nitric Oxide Synthase 3 (Endothelial Cell) (NOS3) antibody
|Synonyms||NOS, INOS, NOS2A, HEP-NOS, iNOS, Nos-2, Nos2a, i-NOS, NOS-II, eNOS, Nos-3, ecNOS, 2310065A03Rik, iNos, cNOS, EC-NOS, NOSIII, NOS3, NOS2, nos2, ECNOS|
Alternatives Immunohistochemistry (IHC), ELISA
|3 references available|
|Price||357.50 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 2 to 3 Business Days|
|Immunogen||Purified recombinant fragment of human eNOS expressed in E. Coli.|
|Description||Other names: ECNOS, NOS3|
|Characteristics||Mouse Monoclonal Antibody to eNOS|
|Specificity||Purified recombinant fragment of human eNOS expressed in E. Coli.|
|Molecular Weight||133289 DA|
Background: Endothelial nitric-oxide synthase (eNOS), also known as NOS3, it is an important enzyme in the cardiovascular system. It is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide is synthesized from L-arginine by nitric oxide synthases. Variations in this gene are associated with susceptibility to coronary spasm.
|Application Notes||[The suggested dilution is:, ELISA: ~~ 1:10000., Immunohistochemistry: ~~ 1:200 - 1000.]|
|Buffer||Purified recombinant fragment of human eNOS expressed in E. Coli.|
|Storage||eNOS Antibody can be stored at 4?, for long term storage, store at -20?.|
|Research Area||Phospho-specific antibodies, Metabolism, Cell Structure|
|Restrictions||For Research Use only|
Dimmeler, Fleming, Fisslthaler et al.: "Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation." in: Nature, Vol. 399, Issue 6736, pp. 601-5, 1999 (PubMed).
Lahiri, Martin: "Reduced expression of endothelial and inducible nitric oxide synthase in a multidrug resistant variant of the MCF-7 human breast cancer cell line." in: Oncology reports, Vol. 12, Issue 5, pp. 1007-11, 2004 (PubMed).
Moreno: "Genetic polymorphisms and haplotypes of eNOS in breast cancer." in: Breast cancer research and treatment, Vol. 109, Issue 1, pp. 181-2, 2008 (PubMed).