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Nitric Oxide Synthase 3 (Endothelial Cell) (NOS3) antibody

Antigen

Nitric Oxide Synthase 3 (Endothelial Cell) (NOS3)
Synonyms NOS, INOS, NOS2A, HEP-NOS, iNOS, Nos-2, Nos2a, i-NOS, NOS-II, eNOS, Nos-3, ecNOS, 2310065A03Rik, iNos, cNOS, EC-NOS, NOSIII, NOS3, NOS2, nos2, ECNOS
Clonality Monoclonal
Host
Alternatives

Mouse
Reactivity
Alternatives

Human
Conjugate
Alternatives Un-conjugated
Application
Alternatives Immunohistochemistry (IHC), ELISA
3 references available
Certificates ISO 9001:2008
Catalog no. ABIN659535
Quantity 0.1ml
Price 357.50 $   Plus shipping costs $45.00
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Additional Information
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Alternative name eNOS
Gene ID 4846
UniProt P29474, NP_001153582.1
Immunogen Purified recombinant fragment of human eNOS expressed in E. Coli.
Isotype IgG1
Description Other names: ECNOS, NOS3
Characteristics Mouse Monoclonal Antibody to eNOS
Specificity Purified recombinant fragment of human eNOS expressed in E. Coli.
Molecular Weight 133289 DA
Comments

Background: Endothelial nitric-oxide synthase (eNOS), also known as NOS3, it is an important enzyme in the cardiovascular system. It is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide is synthesized from L-arginine by nitric oxide synthases. Variations in this gene are associated with susceptibility to coronary spasm.

Application Details
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Application Notes [The suggested dilution is:, ELISA: ~~ 1:10000., Immunohistochemistry: ~~ 1:200 - 1000.]
Buffer Purified recombinant fragment of human eNOS expressed in E. Coli.
Storage eNOS Antibody can be stored at 4?, for long term storage, store at -20?.
Research Area Phospho-specific antibodies, Metabolism, Cell Structure
Restrictions For Research Use only

Publications
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Product Dimmeler, Fleming, Fisslthaler et al.: "Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation." in: Nature, Vol. 399, Issue 6736, pp. 601-5, 1999 (PubMed).

Lahiri, Martin: "Reduced expression of endothelial and inducible nitric oxide synthase in a multidrug resistant variant of the MCF-7 human breast cancer cell line." in: Oncology reports, Vol. 12, Issue 5, pp. 1007-11, 2004 (PubMed).

Moreno: "Genetic polymorphisms and haplotypes of eNOS in breast cancer." in: Breast cancer research and treatment, Vol. 109, Issue 1, pp. 181-2, 2008 (PubMed).

Alternatives
Application Details Publications back to top

Alternatives for antigen "Nitric Oxide Synthase 3 (Endothelial Cell) (NOS3)", type "Antibodies"
Hosts Rabbit (143), Mouse (12)
Reactivities Human (127), Rat (Rattus) (79), Mouse (Murine) (74), Cow (Bovine) (45), Dog (Canine) (39), Pig (Porcine) (35), Guinea Pig (30), Sheep (Ovine) (30), Horse (Equine) (1), Monkey (1)
Applications Western Blotting (WB) (90), ELISA (61), Immunofluorescence (IF) (53), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (27), Immunohistochemistry (IHC) (21), Immunocytochemistry (ICC) (15), Immunoprecipitation (IP) (7), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (5), Flow Cytometry (FACS) (2), Immunohistochemistry (Frozen Sections) (IHC (fro)) (2), Dot Blot (Dot) (1), Immunoelectron Microscopy (IEM) (1), Radioimmunoassay (RIA) (1)
Conjugates Alexa Fluor 350 (4), Alexa Fluor 488 (4), Alexa Fluor 555 (4), Alexa Fluor 647 (4), Biotin (4), PE,Cy5.5 (4), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy7 (1)
Epitopes pSer1177 (13), C-Term (8), N-Term (5), pSer1176 (5), pThr495 (5), Ser1177 (4), pThr113 (4), pThr494 (3), AA 1181-1194 (2), Internal Region (2), AA 106-118 (1), AA 1179-1194 (1), AA 1186-1203 (1), AA 1202-1205 (1), AA 2-11 (1), AA 597-611 (1), Center (1), Ser116 (1), pSer113 (1), pSer114 (1), pSer116 (1), pSer1179 (1), pSer396 (1), pSer615 (1), pSer617 (1), pSer635 (1), pThr674 (1)