DKK1 Protein (AA 32-266) (His tag)
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- Target See all DKK1 Proteins
- DKK1 (Dickkopf Homolog 1 (DKK1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 32-266
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Origin
- Human
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Source
- Hi-5 Cells
- Purification tag / Conjugate
- This DKK1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- Dkk-1, 32-266aa, Human, His-tagged, Recombinant, Hi-5 cell
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product DKK1 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In PBS (pH 7.4) containing 10% glycerol
- Storage
- 4 °C
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- Target
- DKK1 (Dickkopf Homolog 1 (DKK1))
- Alternative Name
- Dkk-1 (DKK1 Products)
- Synonyms
- DKK-1 Protein, SK Protein, AI414495 Protein, SGY Protein, SGY-1 Protein, SGY1 Protein, Soggy Protein, mSgy Protein, dkk1 Protein, dkk Protein, dkk-1 Protein, xdkk1 Protein, Xdkk-1 Protein, Dickkopf1 Protein, dickkopf-1 Protein, mdkk-1 Protein, dkk1-A Protein, dickkopf WNT signaling pathway inhibitor 1 Protein, dickkopf like acrosomal protein 1 Protein, dickkopf-related protein 1 Protein, dickkopf-like 1 Protein, dickkopf WNT signaling pathway inhibitor 1b Protein, dickkopf protein Protein, dickkopf WNT signaling pathway inhibitor 1 S homeolog Protein, DKK1 Protein, Dkk1 Protein, DKKL1 Protein, LOC100228789 Protein, Dkkl1 Protein, dkk1b Protein, dkk1 Protein, dickkopf Protein, dkk1.S Protein
- Background
- Dickkopf-related protein 1, also known as Dkk-1, is a member of the Dkk protein family including Dkk-1, 2, 3 and -4. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated level of Dkk-1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma. Recombinant human Dkk-1 protein, fused to His-tag at C-terminus, was expressed in Hi-5 cell using baculovirus expression system and purified by using conventional chromatography. Synonyms: Dickkopf-1, hDkk-1, SK, Dickkopf-related protein 1 Dickkopf 1, Dickkopf 1 like, Dickkopf homolog 1, Dickkopf related protein 1, DKK 1, hDkk 1, DKK1. NCBI no.: NP_036374
- Molecular Weight
- 27.8 kDa (253 aa) (Molecular weight on SDS-PAGE will appear higher)
- Pathways
- WNT Signaling, Regulation of Muscle Cell Differentiation, Positive Regulation of fat Cell Differentiation
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