DTYMK Protein (AA 1-212) (His tag)

Catalog No. ABIN667491

Product Details

Target: DTYMK (Deoxythymidylate Kinase (Thymidylate Kinase) (DTYMK))

Protein Type: Recombinant

Protein Characteristics: AA 1-212

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This DTYMK protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Characteristics: DTYMK, 1-212aa, Human, His tag, E.coli

Purity: > 95 % by SDS - PAGE

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 20% glycerol, 2mM DTT, 0.1M NaCl

Storage: 4 °C

Target Details

Target: DTYMK (Deoxythymidylate Kinase (Thymidylate Kinase) (DTYMK))

Alternative Name: DTYMK (DTYMK Products)

Synonyms: tymk Protein, wu:fa12c02 Protein, wu:fb14h07 Protein, wu:ft84f02 Protein, zgc:123174 Protein, DTYMK Protein, MGC81047 Protein, Tb08.28L1.680 Protein, Tb08.10J17.310 Protein, DDBDRAFT_0188698 Protein, DDBDRAFT_0230101 Protein, DDB_0188698 Protein, DDB_0230101 Protein, AU044245 Protein, CDC8 Protein, D10Ertd203e Protein, TMPK Protein, TYPK Protein, Tmk Protein, mtmk Protein, PP3731 Protein, TYMK Protein, deoxythymidylate kinase Protein, deoxythymidylate kinase (thymidylate kinase) Protein, deoxythymidylate kinase S homeolog Protein, thymidylate kinase Protein, dTMP kinase Protein, Dtymk Protein, dtymk Protein, DTYMK Protein, dtymk.S Protein, Tmk Protein, CNC04630 Protein, Tb927.8.3510 Protein, Tb927.8.3910 Protein, Ndas_4954 Protein, Mesil_2461 Protein, Slip_0046 Protein, Trad_0568 Protein, Olsu_1446 Protein, Acear_0042 Protein, Igag_1070 Protein, LOC100195817 Protein

Background: DTYMK is also known as thymidylate kinase family and is involved in pyrimidine metabolism. Specifically, DTYMK catalyzes the ATP-dependent conversion of dTMP (deoxythymidine monophosphate) to dTDP (deoxythymidine diphosphate), which then functions as one of the four nucleotides in DNA. Via its role in the catalytic creation of dTDP, DTYMK plays an important role in the pathway of DNA synthesis and is thought to be involved in cell cycle progression and cell growth. Recombinant human DTYMK protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Thymidylate kinase, CDC8, FLJ44192, MGC198617, PP3731, TMPK, TYMK. NCBI no.: NP_036277

Molecular Weight: 26 kDa (232aa), confirmed by MALDI-TOF

Pathways: Nucleotide Phosphorylation