Betacellulin Protein (BTC) (AA 32-111) (His tag)
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- Target See all Betacellulin (BTC) Proteins
- Betacellulin (BTC)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 32-111
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Betacellulin protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- BTC, 32-111aa, Human, His tag, E.coli
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product BTC Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 5mM DTT, 20% glycerol, 200mM NaCl
- Storage
- 4 °C
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- Target
- Betacellulin (BTC)
- Alternative Name
- BTC (BTC Products)
- Synonyms
- BTC Protein, LOC100228121 Protein, probetacellulin Protein, Bcn Protein, betacellulin Protein, betacellulin, epidermal growth factor family member Protein, BTC Protein, LOC100228121 Protein, Btc Protein
- Background
- BTC (Betacellulin) is a member of the EGF family of growth factors and contains 1 EGF-like domain. It is synthesized primarily as a transmembrane precursor, which is then processed to mature molecule by proteolytic events. This protein is a ligand for the EGF receptor. The effects of BTC are probably mediated by the EGF receptor and other related receptors. Recombinant human BTC protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Betacellulin, probetacellulin precursor. NCBI no.: NP_001720
- Molecular Weight
- 11.3kD (101aa), confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
- Pathways
- RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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