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Ghrelin antibody (AA 31-117)

GHRL Reactivity: Human, Rat WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN668991
  • Target See all Ghrelin (GHRL) Antibodies
    Ghrelin (GHRL)
    Binding Specificity
    • 16
    • 14
    • 9
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 31-117
    Reactivity
    • 87
    • 51
    • 24
    • 3
    • 2
    • 1
    Human, Rat
    Host
    • 87
    • 18
    • 6
    • 1
    • 1
    Rabbit
    Clonality
    • 96
    • 17
    Polyclonal
    Conjugate
    • 48
    • 10
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This Ghrelin antibody is un-conjugated
    Application
    • 70
    • 50
    • 32
    • 25
    • 25
    • 19
    • 16
    • 11
    • 7
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Cross-Reactivity
    Human, Rat
    Predicted Reactivity
    Mouse,Dog,Cow,Sheep,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Ghrelin
    Isotype
    IgG
    Top Product
    Discover our top product GHRL Primary Antibody
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Liu, Liu, Li, Chen, Gu et al.: "Ghrelin protects the myocardium with hypoxia/reoxygenation treatment through upregulating the expression of growth hormone, growth hormone secretagogue receptor and insulin-like growth factor-1, and ..." in: International journal of molecular medicine, Vol. 42, Issue 6, pp. 3037-3046, (2019) (PubMed).

    Wölnerhanssen, Moran, Burdyga, Meyer-Gerspach, Peterli, Manz, Thumshirn, Daly, Beglinger, Shirazi-Beechey: "Deregulation of transcription factors controlling intestinal epithelial cell differentiation; a predisposing factor for reduced enteroendocrine cell number in morbidly obese individuals." in: Scientific reports, Vol. 7, Issue 1, pp. 8174, (2017) (PubMed).

    Dai, Jiang, Yuan, Yang, Yang, Huang: "Effects of zearalenone-diet on expression of ghrelin and PCNA genes in ovaries of post-weaning piglets." in: Animal reproduction science, Vol. 168, pp. 126-37, (2016) (PubMed).

    Lemarié, Beauchamp, Dayot, Duby, Legrand, Rioux: "Dietary Caprylic Acid (C8:0) Does Not Increase Plasma Acylated Ghrelin but Decreases Plasma Unacylated Ghrelin in the Rat." in: PLoS ONE, Vol. 10, Issue 7, pp. e0133600, (2015) (PubMed).

    Wang, Song, Li, Liu, Ma, Mao, Wu, Wu, Li, Guan, Liu: "Effects of Wen Dan Tang on insomnia-related anxiety and levels of the brain-gut peptide Ghrelin." in: Neural regeneration research, Vol. 9, Issue 2, pp. 205-12, (2014) (PubMed).

  • Target
    Ghrelin (GHRL)
    Alternative Name
    Ghrelin (GHRL Products)
    Synonyms
    2210006E23Rik antibody, Ghr antibody, MTLRP antibody, MTLRPAP antibody, m46 antibody, Gh1-1 antibody, GRHL antibody, MTLRP-AP antibody, GHR antibody, ghrelin antibody, ghrelin and obestatin prepropeptide antibody, ghrelin/obestatin prepropeptide antibody, Ghrl antibody, GHRL antibody, ghrl antibody
    Background

    Synonyms: MTLRP, Appetite-regulating hormone, Growth hormone secretagogue, Growth hormone-releasing peptide, Motilin-related peptide, Protein M46, GHRL, UNQ524/PRO1066

    Background: Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation. Obestatin may be the ligand for GPR39. May have an appetite-reducing effect resulting in decreased food intake. May reduce gastric emptying activity and jejunal motility (By similarity).

    Gene ID
    51738
    UniProt
    Q9UBU3
    Pathways
    Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Peptide Hormone Metabolism, Negative Regulation of Hormone Secretion, Synaptic Membrane, Feeding Behaviour
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