Slco1a1 antibody (AA 2-90)

Catalog No. ABIN670791

Product Details anti-Slco1a1 Antibody

Target: Slco1a1 (Solute Carrier Organic Anion Transporter Family, Member 1a1 (Slco1a1))

Binding Specificity: AA 2-90

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Slco1a1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from rat Slco1a1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-Slco1a1 antibody (ABIN670791)

Zhu, Dong, Na, Han, Wei, Chen: "Saponins extracted from Dioscorea collettii rhizomes regulate the expression of urate transporters in chronic hyperuricemia rats." in: Biomedicine & pharmacotherapy, Vol. 93, pp. 88-94, (2017) (PubMed).

Pang, Fang, Chen, Zhu, Shan, Su, Yu, Li, Yang, Chen, Liang, Hu, Lv: "Gypenosides Inhibits Xanthine Oxidoreductase and Ameliorates Urate Excretion in Hyperuricemic Rats Induced by High Cholesterol and High Fat Food (Lipid Emulsion)." in: Medical science monitor : international medical journal of experimental and clinical research, Vol. 23, pp. 1129-1140, (2017) (PubMed).

Enoki, Watanabe, Arake, Sugimoto, Imafuku, Tominaga, Ishima, Kotani, Nakajima, Tanaka, Matsushita, Fukagawa, Otagiri, Maruyama: "Indoxyl sulfate potentiates skeletal muscle atrophy by inducing the oxidative stress-mediated expression of myostatin and atrogin-1." in: Scientific reports, Vol. 6, pp. 32084, (2016) (PubMed).

Xu, Zhu, Chan, Lu, Shen, Gillies, Zhou: "The Altered Renal and Hepatic Expression of Solute Carrier Transporters (SLCs) in Type 1 Diabetic Mice." in: PLoS ONE, Vol. 10, Issue 3, pp. e0120760, (2015) (PubMed).

Target Details for Slco1a1

Target: Slco1a1 (Solute Carrier Organic Anion Transporter Family, Member 1a1 (Slco1a1))

Alternative Name: Slco1a1 (Slco1a1 Products)

Synonyms: A530084B21 antibody, OATP-1 antibody, Oatp1 antibody, Oatp1a1 antibody, Slc21a1 antibody, Slc21a3 antibody, solute carrier organic anion transporter family, member 1a1 antibody, Slco1a1 antibody

Background:

Synonyms: Oatp1, OATP-1, Slc21a1, Slc21a3, Solute carrier organic anion transporter family member 1A1, Organic anion-transporting polypeptide 1, Sodium-independent organic anion transporter 1, Solute carrier family 21 member 1, Slco1a1, Oatp1a1

Background: Mediates the Na(+)-independent transport of organic anions such as bromosulfobromophthalein (BSP) and conjugated (taurocholate) and unconjugated (cholate) bile acids.

Gene ID: 50572

UniProt: P46720