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VTCN1 antibody (AA 50-100)

VTCN1 Reactivity: Human ELISA, FACS, IF (p), IF (cc), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN671736
  • Target See all VTCN1 Antibodies
    VTCN1 (V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1))
    Binding Specificity
    • 15
    • 15
    • 7
    • 7
    • 7
    • 6
    • 6
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 50-100
    Reactivity
    • 78
    • 20
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 70
    • 7
    • 2
    Rabbit
    Clonality
    • 66
    • 12
    • 1
    Polyclonal
    Conjugate
    • 27
    • 11
    • 8
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This VTCN1 antibody is un-conjugated
    Application
    • 55
    • 34
    • 26
    • 25
    • 24
    • 15
    • 7
    • 7
    • 7
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    ELISA, Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Cross-Reactivity
    Human
    Predicted Reactivity
    Mouse,Rat,Dog
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from Rat B7H4
    Isotype
    IgG
  • Application Notes
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Maskey, Li, Hu, Xu, Peng, Yu, Cao, Chen, Li, Yang: "Impact of neoadjuvant chemotherapy on lymphocytes and co-inhibitory B7-H4 molecule in gastric cancer: low B7-H4 expression associates with favorable prognosis." in: Tumour biology, (2014) (PubMed).

  • Target
    VTCN1 (V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1))
    Alternative Name
    B7H4 (VTCN1 Products)
    Synonyms
    B7h4 antibody, B7s1 antibody, B7x antibody, BC032925 antibody, B7-H4 antibody, B7H4 antibody, B7S1 antibody, B7X antibody, B7h.5 antibody, PRO1291 antibody, VCTN1 antibody, RGD1311204 antibody, V set domain containing T cell activation inhibitor 1 L homeolog antibody, V-set domain containing T cell activation inhibitor 1 antibody, V-set domain containing T-cell activation inhibitor 1 antibody, V set domain containing T cell activation inhibitor 1 antibody, vtcn1.L antibody, VTCN1 antibody, vtcn1 antibody, Vtcn1 antibody
    Background

    Synonyms: RGD1311204, V-set domain-containing T-cell activation inhibitor 1, Vtcn1

    Background: Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. Involved in promoting epithelial cell transformation (By similarity).

    Gene ID
    295322
    UniProt
    Q501W4
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