TRADD antibody (TNFRSF1A-Associated Via Death Domain) (AA 120-170)

Details for Product anti-TRADD Antibody No. ABIN673314, Supplier: Log in to see
Antigen
  • TRADD
  • Hs.89862
  • 9130005N23Rik
  • AA930854
  • wu:fc59e02
  • zgc:103556
  • tradd
  • TNFRSF1A-associated via death domain
  • conjugal transfer protein D
  • tnfrsf1a-associated via death domain
  • tnfrsf1a-associated via death domain protein
  • TRADD
  • LOC100337888
  • traDd
  • Tradd
  • tradd
  • LOC100136668
Alternatives
anti-Human TRADD antibody for Immunohistochemistry (Paraffin-embedded Sections)
Epitope
AA 120-170
16
11
10
10
9
8
5
5
5
3
3
3
2
2
2
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
111
37
26
6
4
3
3
2
Host
Rabbit
97
24
Clonality
Polyclonal
Conjugate
This TRADD antibody is un-conjugated
5
5
2
2
2
2
2
2
2
2
2
2
2
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
102
56
44
35
29
27
19
11
5
2
1
1
1
Options
Supplier
Log in to see
Supplier Product No.
Log in to see
Immunogen KLH conjugated synthetic peptide derived from mouse of mouse TRADD
Isotype IgG
Purification Purified by Protein A.
Alternative Name Tradd (TRADD Antibody Abstract)
Background

Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B (By similarity). The nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARF of CDKN2A by TRIP12: acts by interacting with TRIP12, leading to disrupt interaction between TRIP12 and isoform p19ARF/ARF of CDKN2A.

Subcellular location: Cytoplasm, Nucleus

Synonyms: AA930854, 9130005N23Rik, Tumor necrosis factor receptor type 1-associated DEATH domain protein, TNFR1-associated DEATH domain protein, TNFRSF1A-associated via death domain, Tradd

Gene ID 71609
UniProt Q3U0V2
Research Area Cardiovascular, Atherosclerosis, Apoptosis/Necrosis
Pathways NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Hepatitis C
Application Notes WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months
Supplier Images
Immunohistochemistry (IHC) image for anti-TNFRSF1A-Associated Via Death Domain (TRADD) (AA 120-170) antibody (ABIN673314) Formalin-fixed and paraffin embedded rat pancreas labeled with Anti-TRADD Polyclonal ...
SDS-PAGE (SDS) image for anti-TNFRSF1A-Associated Via Death Domain (TRADD) (AA 120-170) antibody (ABIN673314) L1 human colon carcinoma lysates L2 rat brain lysates probed with Anti TRADD Polyclon...
Immunohistochemistry (IHC) image for anti-TNFRSF1A-Associated Via Death Domain (TRADD) (AA 120-170) antibody (ABIN673314) Formalin-fixed and paraffin embedded rat kidney labeled with Anti-TRADD Polyclonal An...
Product cited in: Chen, Zhang, Zhang, Li, Sun: "Hydrogen sulfide protects against TNF-α induced neuronal cell apoptosis through miR-485-5p/TRADD signaling." in: Biochemical and biophysical research communications, Vol. 478, Issue 3, pp. 1304-9, 2016 (PubMed).

Did you look for something else?