Chemokine (C-C Motif) Ligand 8 (CCL8) antibody

Details for Product No. ABIN676298, Supplier: Log in to see
Antigen
  • HC14
  • MCP-2
  • MCP2
  • SCYA10
  • SCYA8
  • 1810063B20Rik
  • AB023418
  • Mcp2
  • Scya8
  • chemokine (C-C motif) ligand 8
  • monocyte chemoattractant protein-2 precursor
  • CCL8
  • Ccl8
  • MCP-2
Reactivity
Mouse (Murine)
93
50
3
2
1
Host
Rabbit
73
39
15
1
Clonality
Polyclonal
Conjugate
Un-conjugated
15
7
6
4
4
3
3
3
3
3
3
3
3
3
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
103
58
15
13
7
7
4
4
4
3
2
1
1
Options
Supplier
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Immunogen KLH conjugated synthetic peptide derived from mouse MCP-2
Isotype IgG
Purification Purified by Protein A.
Alternative Name Mcp-2/Ccl8 (CCL8 Antibody Abstract)
Background

Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils. May play a role in neoplasia and inflammatory host responses. This protein can bind heparin. The processed form MCP-2(6-76) does not show monocyte chemotactic activity, but inhibits the chemotactic effect most predominantly of CCL7, and also of CCL2 and CCL5 and CCL8.

Subcellular location: Secreted

Synonyms: HC14, MCP2, MCP-2, SCYA8, SCYA10, C-C motif chemokine 8, Monocyte chemoattractant protein 2, Monocyte chemotactic protein 2, Small-inducible cytokine A8, CCL8

Gene ID 6355
UniProt P80075
Application Notes IHC-P 1:100-500
IF(IHC-P) 1:50-200
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months
Product cited in: Terao, Itoi, Matsumura, Yang, Murota, Katayama: "Local Glucocorticoid Activation by 11β-Hydroxysteroid Dehydrogenase 1 in Keratinocytes: The Role in Hapten-Induced Dermatitis." in: The American journal of pathology, Vol. 186, Issue 6, pp. 1499-510, 2016 (PubMed).

Nguyen, Fentress, Qiu, Yun, Cox, Chawla: "Circadian gene Bmal1 regulates diurnal oscillations of Ly6C(hi) inflammatory monocytes." in: Science (New York, N.Y.), Vol. 341, Issue 6153, pp. 1483-8, 2013 (PubMed). Method employed by authors: Flow Cytometry (FACS) (Sample species: Mouse (Murine)).

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