AGTR1a antibody (AA 101-200)

Catalog No. ABIN677873

Product Details anti-AGTR1a Antibody

Target: AGTR1a (Angiotensin II Receptor, Type 1a (AGTR1a))

Binding Specificity: AA 101-200

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AGTR1a antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human of human Angiotensin II type 1A receptor

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-AGTR1a antibody (ABIN677873)

Shimizu, Amano, Ito, Betto, Yamane, Inoue, Nishizawa, Matsui, Kamata, Nakamura, Kitasato, Koizumi, Majima: "Angiotensin II subtype 1a receptor signaling in resident hepatic macrophages induces liver metastasis formation." in: Cancer science, Vol. 108, Issue 9, pp. 1757-1768, (2017) (PubMed).

Liu, Liu, Tanabe, Maeda, Zou, Komano: "Differential effects of angiotensin II receptor blockers on A? generation." in: Neuroscience letters, Vol. 567, pp. 51-6, (2014) (PubMed).

Target Details for AGTR1a

Target: AGTR1a (Angiotensin II Receptor, Type 1a (AGTR1a))

Alternative Name: Angiotensin 2 type 1A receptor (AGTR1a Products)

Synonyms: 1810074K20Rik antibody, AG2S antibody, AI551199 antibody, AT1 antibody, AT1a antibody, AT2R1 antibody, AT2R1A antibody, Agtr-1a antibody, Agtr1 antibody, Angtr-1a antibody, AT1A antibody, AT1R antibody, AT1-R antibody, AGTR1 antibody, angiotensin II receptor, type 1a antibody, angiotensin II receptor type 1 antibody, Agtr1a antibody, AGTR1 antibody

Background:

Synonyms: AT1, AG2S, AT1B, AT1R, AT1AR, AT1BR, AT2R1, HAT1R, AGTR1B, Type-1 angiotensin II receptor, Angiotensin II type-1 receptor, AGTR1, AGTR1A, AT2R1B

Background: Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

Gene ID: 185

UniProt: P30556

Pathways: ACE Inhibitor Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour