NQO1 antibody (NAD(P)H Dehydrogenase, Quinone 1) (AA 240-274)

Details for Product anti-NQO1 Antibody No. ABIN678428, Supplier: Log in to see
Antigen
  • zgc:77191
  • wu:fb63c10
  • nqo1
  • DHQU
  • DIA4
  • DTD
  • NMOR1
  • NMORI
  • QR1
  • Dia4
  • AV001255
  • Dtd
  • Nmo-1
  • Nmo1
  • Nmor1
  • Ox-1
  • Ox1
  • Qr1
  • NADPH-d
  • NAD(P)H dehydrogenase, quinone 1
  • nqo1
  • NQO1
  • Bpet2092
  • Nqo1
Epitope
AA 240-274
33
14
11
9
7
6
5
4
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
223
77
67
39
20
14
7
6
4
3
1
1
Host
Rabbit
94
91
36
2
Clonality
Polyclonal
Conjugate
This NQO1 antibody is un-conjugated
12
6
6
4
3
3
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
198
71
64
56
44
38
37
27
17
12
5
3
2
1
1
1
Options
Supplier
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Supplier Product No.
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Immunogen KLH conjugated synthetic peptide derived from human NQO1
Isotype IgG
Purification Purified by Protein A.
Alternative Name Nqo1 (NQO1 Antibody Abstract)
Background

The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.

Synonyms: DTD, QR1, DHQU, DIA4, NMOR1, NMORI, NAD(P)H dehydrogenase [quinone] 1, Azoreductase, DT-diaphorase, Menadione reductase, NAD(P)H:quinone oxidoreductase 1, Phylloquinone reductase, Quinone reductase 1, NQO1

Gene ID 1728
UniProt P15559
Research Area Signaling, Metabolism
Application Notes WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months
Supplier Images
Immunohistochemistry (IHC) image for anti-NAD(P)H Dehydrogenase, Quinone 1 (NQO1) (AA 240-274) antibody (ABIN678428) Formalin-fixed and paraffin embedded mouse colon carcinoma labeled with Anti-NQO1 Pol...
SDS-PAGE (SDS) image for anti-NAD(P)H Dehydrogenase, Quinone 1 (NQO1) (AA 240-274) antibody (ABIN678428) L1 rat liver lysates L2 rat brain lysates probed with Anti NQO1 Polyclonal Antibody, ...
Product cited in: Shen, Wu, Wang, Zhao, Zhang, Li, Zhao: "Chloroquine attenuates paraquat-induced lung injury in mice by altering inflammation, oxidative stress and fibrosis." in: International immunopharmacology, Vol. 46, pp. 16-22, 2017 (PubMed). Method employed by authors: Western Blotting (WB) (Sample species: Mouse (Murine)).

Wang, Peng, Wei, Wei, Wang, Ma, Yao, Fu, Zu: "Geraniin exerts cytoprotective effect against cellular oxidative stress by upregulation of Nrf2-mediated antioxidant enzyme expression via PI3K/AKT and ERK1/2 pathway." in: Biochimica et biophysica acta, Vol. 1850, Issue 9, pp. 1751-61, 2015 (PubMed). Method employed by authors: Western Blotting (WB) (Sample species: Human).

Zhao, Shi, Li, Li, Zhao: "Silymarin attenuates paraquat-induced lung injury via Nrf2-mediated pathway in vivo and in vitro." in: Clinical and experimental pharmacology & physiology, 2015 (PubMed).

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