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BAX antibody (pSer184)

BAX Reactivity: Human, Mouse, Rat WB, ELISA, FACS, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN682843
  • Target See all BAX Antibodies
    BAX (BCL2-Associated X Protein (BAX))
    Binding Specificity
    • 40
    • 32
    • 20
    • 17
    • 15
    • 11
    • 10
    • 10
    • 9
    • 8
    • 8
    • 7
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer184
    Reactivity
    • 256
    • 155
    • 142
    • 46
    • 31
    • 27
    • 25
    • 18
    • 17
    • 10
    • 9
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 167
    • 97
    • 4
    • 2
    Rabbit
    Clonality
    • 180
    • 90
    Polyclonal
    Conjugate
    • 141
    • 16
    • 13
    • 13
    • 10
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BAX antibody is un-conjugated
    Application
    • 240
    • 113
    • 71
    • 64
    • 52
    • 52
    • 51
    • 43
    • 41
    • 14
    • 12
    • 8
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Human, Mouse, Rat
    Predicted Reactivity
    Dog,Cow,Sheep,Pig
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic phosphopeptide derived from human Bax around the phosphorylation site of Ser184
    Isotype
    IgG
    Top Product
    Discover our top product BAX Primary Antibody
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Park, Park, Kim, Kim, Yoon, Hur: "Berberine induces mitochondrial apoptosis of EBV-transformed B cells through p53-mediated regulation of XAF1 and GADD45α." in: International journal of oncology, Vol. 49, Issue 1, pp. 411-21, (2016) (PubMed).

    Daverey, Agrawal: "Curcumin alleviates oxidative stress and mitochondrial dysfunction in astrocytes." in: Neuroscience, Vol. 333, pp. 92-103, (2016) (PubMed).

    Gao, Zhou, Wang, Lew, Richards, Wang: "Urocortin-2 suppression of p38-MAPK signaling as an additional mechanism for ischemic cardioprotection." in: Molecular and cellular biochemistry, (2014) (PubMed).

    Park, Kim, Kim, Kim, Lee, Cho, Lee, Hur: "Melphalan-induced apoptosis of EBV-transformed B cells through upregulation of TAp73 and XAF1 and nuclear import of XPA." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 191, Issue 12, pp. 6281-91, (2013) (PubMed).

    Pereda: "[Histochemical study of the distribution of sialomucins in the oviducts and jelly coat of the oocytes of Rana pipiens. Behavior of the different layers of the coat in water]." in: Journal of embryology and experimental morphology, Vol. 24, Issue 1, pp. 1-12, (1971) (PubMed).

  • Target
    BAX (BCL2-Associated X Protein (BAX))
    Alternative Name
    Bax (BAX Products)
    Synonyms
    BAX-ALPHA antibody, bax-A antibody, xBax antibody, xlbax antibody, BAX antibody, bax antibody, fj16e01 antibody, wu:fc50b10 antibody, wu:fj16e01 antibody, BCL2L4 antibody, zgc:112983 antibody, BCL2 associated X, apoptosis regulator antibody, BCL2-associated X protein L homeolog antibody, BCL2-associated X protein antibody, bcl2-associated X protein, a antibody, bcl2-associated X protein, b antibody, BAX antibody, bax.L antibody, bax antibody, baxa antibody, Bax antibody, baxb antibody
    Background

    Synonyms: BCL2L4, Apoptosis regulator BAX, Bcl-2-like protein 4, Bcl2-L-4, BAX

    Background: Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.

    Gene ID
    581
    UniProt
    Q07812
    Pathways
    p53 Signaling, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
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