NUCB2 antibody (AA 181-280)

Catalog No. ABIN700690

Product Details anti-NUCB2 Antibody

Target: NUCB2 (NES1) (Nesfatin-1 (NES1))

Binding Specificity: AA 181-280

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NUCB2 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Nesfatin-1/Nucb2

Isotype: IgG

Application Details

Application Notes: FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-NUCB2 antibody (ABIN700690)

Chen, Cao, Chang, Ma, Gao, Tong, Li, Han, Yi: "Increasing hypothalamic nucleobindin 2 levels and decreasing hypothalamic inflammation in obese male mice via diet and exercise alleviate obesity-associated hypogonadism." in: Neuropeptides, Vol. 74, pp. 34-43, (2019) (PubMed).

Jia, Li, Li, Wu, Xie, Lin: "Role of nesfatin-1 in a rat model of visceral hypersensitivity." in: World journal of gastroenterology : WJG, Vol. 19, Issue 22, pp. 3487-93, (2013) (PubMed).

Target Details for NUCB2

Target: NUCB2 (NES1) (Nesfatin-1 (NES1))

Alternative Name: Nesfatin-1 (NES1 Products)

Synonyms: nucleobindin-2 antibody, nucleobindin 2 antibody, NUCB2 antibody, Nucb2 antibody

Background:

Synonyms: NEFA, HEL-S-19, Nucleobindin-2, DNA-binding protein NEFA, Gastric cancer antigen Zg4, Prepronesfatin, NUCB2

Background: Calcium-binding protein. May have a role in calcium homeostasis. Nesfatin-1: Anorexigenic peptide, seems to play an important role in hypothalamic pathways regulating food intake and energy homeostasis, acting in a leptin-independent manner. May also exert hypertensive roles and modulate blood pressure through directly acting on peripheral arterial resistance (By similarity).

Gene ID: 4925

UniProt: P80303