X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 3 (XRCC3) antibody (Biotin)

Antigen: X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 3 (XRCC3)

Synonyms: AI182522, AW537713, 4432412E01Rik, MGC69118, im:7142103, zgc:101608, si:dkey-11b8.1, xrcc3, XRCC3, MGC142843

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse (Murine)

Conjugate: Biotin

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Flow Cytometry (FACS), Immunofluorescence (IF)

Catalog no.: ABIN706048

Additional Information

Alternative name: XRCC3

Immunogen: Polyclonal antibodies are produced by immunizing animals with synthetic peptide derived from human XRCC3

Format: Lyophilized

Reconstitution: Reconstitute with 100ul sterille distilled water. After reconstitution, stock concentration=1ug/1ul, preservatives included (BSA=10ug/ul, Sodium azide=0.1%)

Isotype: IgG

Description: Synonym: DNA repair protein XRCC3, RAD51 like, X ray repair complementing defective repair in Chinese hamster, X ray repair complementing defective repair in Chinese hamster cells 3, X ray repair cross complementing protein 3, X-ray repair cross-complementing protein 3, XRCC 3, XRCC3, XRCC3_HUMAN.

Molecular Weight: 38kDa

Comments:

Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA

thought to repair chromosomal fragmentation

translocations and deletions. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51 and RAD51C.

Application Details

Application Notes: WB (1:100-500), ELISA (1:500-1000), IP (1:20-100), IHC-P (1:100-500), IHC-F (1:100-500), Flow-Cyt (1:20-100), IF (1:50-200)

Concentration: 1mg/1ml

Purification: Antibodies are purified by protein A and peptide affinity chromatography.

Buffer: 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide

Storage: Ship at room temperature. Store at -20°C

Research Area: Chromatin and Nuclear Signaling, Chromatin Binding Proteins, DNA/RNA

Restrictions: For Research Use only