MACC1 antibody (AA 761-852) (HRP)

Catalog No. ABIN706535

Product Details anti-MACC1 Antibody (HRP)

Target: MACC1 (Metastasis Associated in Colon Cancer 1 (MACC1))

Binding Specificity: AA 761-852

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MACC1 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse,Cow

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MACC1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for MACC1

Target: MACC1 (Metastasis Associated in Colon Cancer 1 (MACC1))

Alternative Name: MACC1 (MACC1 Products)

Synonyms: 7A5 antibody, SH3BP4L antibody, 4732474O15Rik antibody, Gm267 antibody, 7a5 antibody, RGD1309838 antibody, MACC1, MET transcriptional regulator antibody, metastasis associated in colon cancer 1 antibody, MACC1 antibody, Macc1 antibody

Background:

Synonyms: 7A5, SH3BP4L, Metastasis-associated in colon cancer protein 1, SH3 domain-containing protein 7a5, MACC1

Background: Acts as a transcription activator for MET and as a key regulator of HGF-MET signaling. Promotes cell motility, proliferation and hepatocyte growth factor (HGF)-dependent scattering in vitro and tumor growth and metastasis in vivo.

Gene ID: 346389

UniProt: Q6ZN28