PTPN13 antibody (AA 801-900)

Catalog No. ABIN714341

Product Details anti-PTPN13 Antibody

Target: PTPN13 (Protein tyrosine Phosphatase, Non-Receptor Type 13 (APO-1/CD95 (Fas)-Associated Phosphatase) (PTPN13))

Binding Specificity: AA 801-900

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTPN13 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FAP1/PTPN13

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-PTPN13 antibody (ABIN714341)

Evrard, Lecce, Michelis, Nomura-Kitabayashi, Pandey, Purushothaman, dEscamard, Li, Hadri, Fujitani, Moreno, Benard, Rimmele, Cohain, Mecham, Randolph, Nabel, Hajjar, Fuster, Boehm, Kovacic: "Endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instability." in: Nature communications, Vol. 7, pp. 11853, (2016) (PubMed).

Target Details for PTPN13

Target: PTPN13 (Protein tyrosine Phosphatase, Non-Receptor Type 13 (APO-1/CD95 (Fas)-Associated Phosphatase) (PTPN13))

Alternative Name: FAP1 (PTPN13 Products)

Synonyms: FAP-1 antibody, PNP1 antibody, PTP-BAS antibody, PTP-BL antibody, PTP1E antibody, PTPL1 antibody, PTPLE antibody, hPTP1E antibody, PTPN13 antibody, AI324989 antibody, Ptpri antibody, RIP antibody, Ptp-bl antibody, ptp antibody, wu:fb50g04 antibody, zgc:162319 antibody, protein tyrosine phosphatase, non-receptor type 13 antibody, tyrosine-protein phosphatase non-receptor type 13 antibody, PTPN13 antibody, LOC100540743 antibody, ptpn13 antibody, Ptpn13 antibody

Background:

Synonyms: PNP1, FAP-1, PTP1E, PTPL1, PTPLE, PTP-BL, hPTP1E, PTP-BAS, Tyrosine-protein phosphatase non-receptor type 13, Fas-associated protein-tyrosine phosphatase 1, Protein-tyrosine phosphatase 1E, PTP-E1, hPTPE1, Protein-tyrosine phosphatase PTPL1, PTPN13

Background: Tyrosine phosphatase which regulates negatively FAS-induced apoptosis and NGFR-mediated pro-apoptotic signaling (PubMed:15611135). May regulate phosphoinositide 3-kinase (PI3K) signaling through dephosphorylation of PIK3R2 (PubMed:23604317).

Gene ID: 5783

UniProt: Q12923