Phosducin-Like antibody (AA 51-150) (HRP)

Catalog No. ABIN715130

Product Details anti-Phosducin-Like Antibody (HRP)

Target: Phosducin-Like (PDCL)

Binding Specificity: AA 51-150

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Phosducin-Like antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PHLP

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Phosducin-Like

Target: Phosducin-Like (PDCL)

Alternative Name: PHLP (PDCL Products)

Synonyms: PhLP antibody, Phlp antibody, 1200011E13Rik antibody, AW108059 antibody, PhLP1 antibody, fc06a08 antibody, im:6793474 antibody, wu:fc06a08 antibody, zgc:73264 antibody, phosducin like antibody, phosducin-like antibody, PDCL antibody, Pdcl antibody, pdcl antibody

Background:

Synonyms: PhLP, Phosducin-like protein, PDCL, PHLOP1, PhLP1

Background: Isoform 1: Functions as a co-chaperone for CCT in the assembly of heterotrimeric G protein complexes, facilitates the assembly of both Gbeta-Ggamma and RGS-Gbeta5 heterodimers. Isoform 2: Acts as a negative regulator of heterotrimeric G proteins assembly by trapping the preloaded G beta subunits inside the CCT chaperonin.

Gene ID: 5082

UniProt: Q13371