ENTPD5 antibody (AA 331-380)

Catalog No. ABIN717596

Product Details anti-ENTPD5 Antibody

Target: ENTPD5 (Ectonucleoside Triphosphate diphosphohydrolase 5 (ENTPD5))

Binding Specificity: AA 331-380

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ENTPD5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat,Cow,Sheep,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ENTPD5/CD39L4

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for ENTPD5

Target: ENTPD5 (Ectonucleoside Triphosphate diphosphohydrolase 5 (ENTPD5))

Alternative Name: CD39L4 (ENTPD5 Products)

Synonyms: ENTPD5 antibody, CD39L4 antibody, NTPDase-5 antibody, PCPH antibody, AI196558 antibody, AI987697 antibody, Cd39l4 antibody, ER-UDPase antibody, NTPDase5 antibody, Pcph antibody, mNTPase antibody, cph antibody, ectonucleoside triphosphate diphosphohydrolase 5 antibody, ectonucleoside triphosphate diphosphohydrolase 5 L homeolog antibody, ENTPD5 antibody, entpd5 antibody, entpd5.L antibody, Entpd5 antibody

Background:

Synonyms: PCPH, CD39L4, NTPDase-5, Ectonucleoside triphosphate diphosphohydrolase 5, NTPDase 5, CD39 antigen-like 4, ER-UDPase, Guanosine-diphosphatase ENTPD5, GDPase ENTPD5, Nucleoside diphosphatase, Uridine-diphosphatase ENTPD5, UDPase ENTPD5, ENTPD5

Background: Uridine diphosphatase (UDPase) that promotes protein N-glycosylation and ATP level regulation. UDP hydrolysis promotes protein N-glycosylation and folding in the endoplasmic reticulum, as well as elevated ATP consumption in the cytosol via an ATP hydrolysis cycle. Together with CMPK1 and AK1, constitutes an ATP hydrolysis cycle that converts ATP to AMP and results in a compensatory increase in aerobic glycolysis. The nucleotide hydrolyzing preference is GDP > IDP > UDP, but not any other nucleoside di-, mono- or triphosphates, nor thiamine pyrophosphate. Plays a key role in the AKT1-PTEN signaling pathway by promoting glycolysis in proliferating cells in response to phosphoinositide 3-kinase (PI3K) signaling.

Gene ID: 957

UniProt: O75356