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Sodium Channel, Voltage-Gated, Type I, beta (SCN1B) antibody (RBITC)

Antigen

Sodium Channel, Voltage-Gated, Type I, beta (SCN1B)

Synonyms GEFSP1
Clonality Polyclonal
Host
Alternatives

Rabbit

Reactivity
Alternatives

Human, Mouse (Murine), Rat (Rattus)

Conjugate
Alternatives RBITC
Application
Alternatives Flow Cytometry (FACS), Immunofluorescence (IF)
Catalog no. ABIN719980
Quantity 100 µg  (1mg/1ml)
Price 290.00 $   Plus shipping costs $35.00
Shipping to
Availability Ships within 10 to 15 Business Days

Additional Information

Alternative name SCN1B
Immunogen Polyclonal antibodies are produced by immunizing animals with synthetic peptide derived from hu SCN1B
Format Lyophilized
Reconstitution Reconstitute with 100ul sterille distilled water. After reconstitution, stock concentration=1ug/1ul, preservatives included (BSA=10ug/ul, Sodium azide=0.1%)
Isotype IgG
Description Synonym: GEFSP1, SCN1B, SCN1B_HUMAN, sodium channel beta 1 subunit, Sodium channel subunit beta 1, Sodium channel subunit beta-1, Sodium channel voltage gated type I beta.
Specificity Excitation / Emission Wavelengths: 495nm/519nm
Molecular Weight 25kDa
Comments

Crucial in the assembly

expression

and functional modulation of the heterotrimeric complex of the sodium channel. The subunit beta-1 can modulate multiple alpha subunit isoforms from brain

skeletal muscle

and heart. Its association with neurofascin may target the sodium channels to the nodes of Ranvier of developing axons and retain these channels at the nodes in mature myelinated axons.. Tissue specificity

_x000D_ Abundantly expressed in skeletal muscle

heart and brain.

Application Details

Application Notes Flow-Cyt (1:50-200), IF (1:50-200)
Concentration 1mg/1ml
Purification Antibodies are purified by protein A and peptide affinity chromatography.
Buffer Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
Storage Ship at room temperature. Store at -20°C
Research Area Signaling, Metabolism
Restrictions For Research Use only

Alternatives

Alternatives for antigen "Sodium Channel, Voltage-Gated, Type I, beta (SCN1B)", type "Antibodies"
Hosts Rabbit (23)
Reactivities Human (22), Mouse (Murine) (19), Rat (Rattus) (19), Cow (Bovine) (2), Dog (Canine) (2), Horse (Equine) (2), Pig (Porcine) (2)
Applications Flow Cytometry (FACS) (17), Immunofluorescence (IF) (17), Western Blotting (WB) (7), ELISA (4), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (2), Immunoprecipitation (IP) (2), Immunoelectron Microscopy (IEM) (1)
Conjugates Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)