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IFNAR2 antibody (AA 165-260)

IFNAR2 Reactivity: Human, Rat WB, ELISA, IHC (p), IHC (fro), IF (cc), IF (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN721825
  • Target See all IFNAR2 Antibodies
    IFNAR2 (Interferon alpha/beta Receptor 2 (IFNAR2))
    Binding Specificity
    • 9
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 165-260
    Reactivity
    • 30
    • 6
    • 3
    Human, Rat
    Host
    • 23
    • 3
    • 3
    • 1
    • 1
    • 1
    Rabbit
    Clonality
    • 31
    • 2
    Polyclonal
    Conjugate
    • 21
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IFNAR2 antibody is un-conjugated
    Application
    • 18
    • 12
    • 8
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Human, Rat
    Predicted Reactivity
    Mouse
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from mouse IFNAR2
    Isotype
    IgG
    Top Product
    Discover our top product IFNAR2 Primary Antibody
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Lopušná, Benkóczka, Lupták, Matúšková, Lukáčiková, Ovečková, Režuchová: "Murine gammaherpesvirus targets type I IFN receptor but not type III IFN receptor early in infection." in: Cytokine, Vol. 83, pp. 158-70, (2016) (PubMed).

  • Target
    IFNAR2 (Interferon alpha/beta Receptor 2 (IFNAR2))
    Alternative Name
    IFNAR2 (IFNAR2 Products)
    Synonyms
    AI747302 antibody, Ifnar-2 antibody, IFN-R antibody, IFN-alpha-REC antibody, IFNABR antibody, IFNARB antibody, IFN-R-2 antibody, IFNBR antibody, interferon alpha and beta receptor subunit 2 antibody, interferon (alpha and beta) receptor 2 antibody, IFNAR2 antibody, Ifnar2 antibody
    Background

    Synonyms: Ifnar-2, AI747302, Interferon alpha/beta receptor 2, IFN-R-2, IFN-alpha/beta receptor 2, Type I interferon receptor 2, Ifnar2

    Background: Associates with IFNAR1 to form the type I interferon receptor. Receptor for interferons alpha and beta. Involved in IFN-mediated STAT1, STAT2 and STAT3 activation. Isoform 1 and isoform 2 are directly involved in signal transduction due to their association with the TYR kinase, JAK1. Isoform 2 and 3 may be potent inhibitors of type I IFN receptor activity (By similarity).

    Gene ID
    15976
    UniProt
    O35664
    Pathways
    JAK-STAT Signaling, Hepatitis C
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