Melatonin Receptor 1A antibody (AA 201-280)

Catalog No. ABIN723815

Product Details anti-Melatonin Receptor 1A Antibody

Target: Melatonin Receptor 1A (MTNR1A)

Binding Specificity: AA 201-280

Reactivity: Human, Mouse, Rat, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Melatonin Receptor 1A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Dot Blot (DB)

Cross-Reactivity: Cow, Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Sheep,Pig,Chicken,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MTR-1A

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
dot-blot()

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-Melatonin Receptor 1A antibody (ABIN723815)

Yang, Tang, Wang, Zhang, Zan: "Melatonin promotes triacylglycerol accumulation via MT2 receptor during differentiation in bovine intramuscular preadipocytes." in: Scientific reports, Vol. 7, Issue 1, pp. 15080, (2019) (PubMed).

Tabecka-Lonczynska, Mytych, Solek, Kulpa, Koziorowski: "New insight on the role of melatonin receptors in reproductive processes of seasonal breeders on the example of mature male European bison (Bison bonasus, Linnaeus 1758)." in: Journal of photochemistry and photobiology. B, Biology, Vol. 173, pp. 84-91, (2017) (PubMed).

Jang, Na, Hong, Lee, Moon, Cho, Park, Lee, Chang, Lee, Ko, Lee, Choi: "Synergistic effect of melatonin and ghrelin in preventing cisplatin-induced ovarian damage via regulation of FOXO3a phosphorylation and binding to the p27Kip1promoter in primordial follicles." in: Journal of pineal research, Vol. 63, Issue 3, (2017) (PubMed).

Wang, Liu, Wu, Ma, Ahmad, Liu, Han, Jiang, Zhang, Yang: "Melatonin suppresses apoptosis and stimulates progesterone production by bovine granulosa cells via its receptors (MT1 and MT2)." in: Theriogenology, Vol. 78, Issue 7, pp. 1517-26, (2012) (PubMed).

Target Details for Melatonin Receptor 1A

Target: Melatonin Receptor 1A (MTNR1A)

Alternative Name: Melatonin Receptor 1A (MTNR1A Products)

Synonyms: MEL-1A-R antibody, MT1 antibody, MTNR1A antibody, MR antibody, MelR antibody, MEL1A antibody, Mel-1A-R antibody, Mel-1A-R-A antibody, Mel1a receptor A antibody, mel1ar antibody, mtnr1ar antibody, zgc:110628 antibody, melatonin receptor 1A antibody, melatonin receptor 1A a antibody, MTNR1A antibody, Mtnr1a antibody, mtnr1aa antibody

Background:

Synonyms: MT1, MEL-1A-R, Melatonin receptor type 1A, Mel1a receptor, MTNR1A

Background: High affinity receptor for melatonin. Likely to mediates the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity.

Gene ID: 4543

UniProt: P48039