ADNP antibody (AA 331-400)

Catalog No. ABIN724040

Product Details anti-ADNP Antibody

Target: ADNP (Activity-Dependent Neuroprotector Homeobox (ADNP))

Binding Specificity: AA 331-400

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADNP antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Dog,Cow,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ADNP

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-ADNP antibody (ABIN724040)

Ma, Chu, Zhang, Jiang, Jia, Dang, Gao: "Intranasal Delivery of Recombinant NT4-NAP/AAV Exerts Potential Antidepressant Effect." in: Neurochemical research, Vol. 41, Issue 6, pp. 1375-80, (2016) (PubMed).

Target Details for ADNP

Target: ADNP (Activity-Dependent Neuroprotector Homeobox (ADNP))

Alternative Name: ADNP (ADNP Products)

Synonyms: AA589558 antibody, mKIAA0784 antibody, ADNP1 antibody, activity-dependent neuroprotective protein antibody, activity dependent neuroprotector homeobox antibody, activity-dependent neuroprotector homeobox antibody, Adnp antibody, ADNP antibody

Background:

Synonyms: Activity dependent neuroprotective protein, Activity dependent neuroprotector, ADNP, NAP, KIAA0784

Background: The activity dependent neuroprotective protein (ADNP) gene is frequently amplified in many neoplasias, including breast, bladder, ovarian, pancreatic, and colon cancers. ADNP mRNA is abundantly expressed in distinct normal tissues, and high expression levels were encountered in malignant cells. ADNP is implicated in maintaining cell survival, perhaps through modulation of p53. The encoded protein contains one homeobox and nine zinc finger domains, suggesting that it functions as a transcription factor.

Gene ID: 23394

UniProt: Q9H2P0

Pathways: Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process