Substance P antibody (AA 58-68)

Catalog No. ABIN724400

Product Details anti-Substance P Antibody

Target: Substance P

Binding Specificity: AA 58-68

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Substance P antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Cow,Sheep,Pig,Horse,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SP

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-Substance P antibody (ABIN724400)

Daschil, Kniewallner, Obermair, Hutter-Paier, Windisch, Marksteiner, Humpel: "L-type calcium channel blockers and substance P induce angiogenesis of cortical vessels associated with beta-amyloid plaques in an Alzheimer mouse model." in: Neurobiology of aging, (2015) (PubMed).

Liu, Peng, Long, Li, Ke, Fang: "Mutual effect between neuropeptides and inflammatory cytokines in neurogenic SMSCs of human temporomandibular joint." in: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, Vol. 34, Issue 4, pp. 602-7, (2014) (PubMed).

Tu, Li, Peng, Hu, Liu, Kong, Liu, Gao, Xu, Xu, Qiu, Fan, Zhu, Yu, Zheng, Wu, Peng, Song, Wu, Liang: "P2X(7) inhibition in stellate ganglia prevents the increased sympathoexcitatory reflex via sensory-sympathetic coupling induced by myocardial ischemic injury." in: Brain research bulletin, Vol. 96, pp. 71-85, (2013) (PubMed).

Liu, Li, Peng, Tu, Kong, Liu, Gao, Xu, Qiu, Fan, Zhu, Yu, Zheng, Wu, Peng, Song, Wu, Li, Liang: "Sensory-sympathetic coupling in superior cervical ganglia after myocardial ischemic injury facilitates sympathoexcitatory action via P2X7 receptor." in: Purinergic signalling, Vol. 9, Issue 3, pp. 463-79, (2013) (PubMed).

Target Details for Substance P

Target: Substance P

Abstract: Substance P Products

Synonyms: Hs.2563 antibody, NK2 antibody, NKNA antibody, NPK antibody, TAC2 antibody, PPTA3 antibody, Ppt5fl antibody, RATPPTA3 antibody, TAC antibody, 4930528L02Rik antibody, NK-1 antibody, NK1 antibody, Nkna antibody, PPT-A antibody, PPTA antibody, SP antibody, PPT antibody, beta-PPT-A antibody, NKA antibody, tachykinin precursor 1 antibody, tachykinin, precursor 1 antibody, tachykinin 1 antibody, TAC1 antibody, Tac1 antibody

Background:

Synonyms: NK2, NPK, NKNA, TAC2, Hs.2563, Protachykinin-1, PPT, TAC1, NKA

Background: Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.

Gene ID: 6863

UniProt: P20366