Platelet-Derived Growth Factor beta Polypeptide (Simian Sarcoma Viral (V-Sis) Oncogene Homolog) (PDGFB) antibody

Antigen: Platelet-Derived Growth Factor beta Polypeptide (Simian Sarcoma Viral (V-Sis) Oncogene Homolog) (PDGFB)

Synonyms: PDGFB, sis, c-sis, pdgf2, MGC83524, si:ch211-79m20.1, si:dkey-261d11.1

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Rat (Rattus), Mouse (Murine), Rabbit, Dog (Canine), Horse (Equine), Cow (Bovine), Sheep (Ovine)

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Flow Cytometry (FACS), Immunofluorescence (IF)

Catalog no.: ABIN725990

Additional Information

Alternative name: PDGF-B

Immunogen: Polyclonal antibodies are produced by immunizing animals with synthetic peptide derived from human PDGF-B C-terminus

Format: Lyophilized

Reconstitution: Reconstitute with 100ul sterille distilled water. After reconstitution, stock concentration=1ug/1ul, preservatives included (BSA=10ug/ul, Sodium azide=0.1%)

Isotype: IgG  (Matching secondary antibodies)

Description: Synonym: PDGF-B, Platelet-derived growth factor B-chain.

Molecular Weight: 27kDa

Comments:

Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. Binding of this growth factor to its affinity receptor elicits a variety of cellular responses. It is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heal the wound. [SUBUNIT] Antiparallel disulfide-linked dimer of nonidentical (A and B) chains. Homodimers of A and B chains are implicated in transformation processes. A-A and B-B

as well as A-B

dimers can bind to the PDGF receptor. Belongs to the PDGF/VEGF growth factor family.

Application Details

Application Notes: WB (1:100-500), ELISA (1:500-1000), IP (1:20-100), IHC-P (1:100-500), IHC-F (1:100-500), Flow-Cyt (1:20-100), IF (1:50-200)

Concentration: 1mg/1ml

Purification: affinity purified by Protein A

Buffer: 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide

Storage: Ship at room temperature. Store at -20°C

Restrictions: For Research Use only