TNNC1 antibody (AA 131-210)

Catalog No. ABIN728308

Product Details anti-TNNC1 Antibody

Target: TNNC1 (Cardiac Troponin C (TNNC1))

Binding Specificity: AA 131-210

Reactivity: Human, Mouse, Rat, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNNC1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human, Mouse, Rabbit, Rat

Predicted Reactivity: Dog,Cow,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Cardiac Troponin I

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-TNNC1 antibody (ABIN728308)

Ruan, Zhu, Yin, Chen: "Inhibitor of p53-p21 pathway induces the differentiation of human umbilical cord derived mesenchymal stem cells into cardiomyogenic cells." in: Cytotechnology, Vol. 68, Issue 4, pp. 1257-65, (2016) (PubMed).

Ruan, Zhu, Yin, Chen: "Overexpressing NKx2.5 increases the differentiation of human umbilical cord drived mesenchymal stem cells into cardiomyocyte-like cells." in: Biomedicine & pharmacotherapy, Vol. 78, pp. 110-5, (2016) (PubMed).

Sharma, Han, Jang: "Rapid electrical immunoassay of the cardiac biomarker troponin I through dielectrophoretic concentration using imbedded electrodes." in: Biosensors & bioelectronics, Vol. 82, pp. 78-84, (2016) (PubMed).

Zhu, Ruan, Yin, Chen: "Expression and significance of DLL4--Notch signaling pathway in the differentiation of human umbilical cord derived mesenchymal stem cells into cardiomyocytes induced by 5-azacytidine." in: Cell biochemistry and biophysics, Vol. 71, Issue 1, pp. 249-53, (2015) (PubMed).

Liu, Li, Sun, Li, Du, Sun, Cao, Li, Jia, Wang, Chang, Yu, Wang, Peng: "The use of antibody modified liposomes loaded with AMO-1 to deliver oligonucleotides to ischemic myocardium for arrhythmia therapy." in: Biomaterials, Vol. 35, Issue 11, pp. 3697-707, (2014) (PubMed).

Zhao, Yang, Zhao: "Rho-associated protein kinases play an important role in the differentiation of rat adipose-derived stromal cells into cardiomyocytes in vitro." in: PLoS ONE, Vol. 9, Issue 12, pp. e115191, (2014) (PubMed).

Gao, Zhang, Ding, Chen, Hu, Jiang, Li, Chen, Wang, Ye, Zhu: "Common expression of stemness molecular markers and early cardiac transcription factors in human Wharton's jelly-derived mesenchymal stem cells and embryonic stem cells." in: Cell transplantation, Vol. 22, Issue 10, pp. 1883-900, (2014) (PubMed).

Target Details for TNNC1

Target: TNNC1 (Cardiac Troponin C (TNNC1))

Alternative Name: cardiac Troponin I (TNNC1 Products)

Synonyms: CMD1Z antibody, CMH13 antibody, TN-C antibody, TNC antibody, TNNC antibody, cTnC antibody, tnnc1 antibody, zgc:103465 antibody, PCTNC1 antibody, cmd1z antibody, cmh13 antibody, tnc antibody, tnnc antibody, MGC80066 antibody, TNNC1 antibody, AI874626 antibody, TnC antibody, cTnI antibody, tncc antibody, Tncc antibody, stnnc antibody, zgc:86932 antibody, troponin C1, slow skeletal and cardiac type antibody, troponin C type 1a (slow) antibody, troponin C type 1 (slow) L homeolog antibody, cardiac troponin C antibody, troponin C, cardiac/slow skeletal antibody, troponin C type 1b (slow) antibody, TNNC1 antibody, tnnc1a antibody, tnnc1.L antibody, tnnc1 antibody, Tnnc1 antibody, tnnc1b antibody

Background:

Synonyms: CMH7, RCM1, cTnI, CMD2A, TNNC1, CMD1FF, Troponin I, cardiac muscle, Cardiac troponin I, TNNI3

Background: Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.

Gene ID: 7137

UniProt: P19429