TNFRSF10B antibody (Tumor Necrosis Factor Receptor Superfamily, Member 10b)

Details for Product anti-TNFRSF10B Antibody No. ABIN733118, Supplier: Log in to see
Antigen
  • TNFRSF10B
  • dr5
  • cd262
  • killer
  • trick2
  • trickb
  • xDR-M1
  • xDR-M2
  • ztnfr9
  • trailr2
  • trick2a
  • trick2b
  • CD262
  • DR5
  • KILLER
  • KILLER/DR5
  • TRAIL-R2
  • TRAILR2
  • TRICK2
  • TRICK2A
  • TRICK2B
  • TRICKB
  • ZTNFR9
  • Ly98
  • MK
  • tumor necrosis factor receptor superfamily, member 10b
  • Tnfrsf10b
  • TNFRSF10B
  • tnfrsf10b-b
  • tnfrsf10b
Alternatives
anti-Rat (Rattus) TNFRSF10B antibody for ELISA
Reactivity
Mouse (Murine), Rat (Rattus)
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75
25
1
1
1
1
1
Host
Rabbit
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169
10
6
6
2
Clonality
Polyclonal
Conjugate
This TNFRSF10B antibody is un-conjugated
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20
16
6
5
5
5
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4
4
4
4
4
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2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
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163
73
52
39
31
26
26
15
13
13
4
4
3
3
2
2
1
Options
Supplier
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Immunogen KLH conjugated synthetic peptide derived from mouse DR5
Isotype IgG
Purification Purified by Protein A.
Alternative Name TRAILR2/DR5/CD262 (TNFRSF10B Antibody Abstract)
Background

Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis (By similarity).

Subcellular location: Cytoplasm

Synonyms: MK, DR5, Ly98, KILLER, TRICKB, TRAILR2, TRICK2A, TRICK2B, Tumor necrosis factor receptor superfamily member 10B, Death receptor 5, CD262, Tnfrsf10b

Gene ID 21933
UniProt Q9QZM4
Pathways p53 Signaling, Apoptosis, Positive Regulation of Endopeptidase Activity
Application Notes WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months
Supplier Images
Immunohistochemistry (IHC) image for anti-TNFRSF10B antibody (Tumor Necrosis Factor Receptor Superfamily, Member 10b) (ABIN733118) Formalin-fixed and paraffin embedded human colon cancer labeled with Anti-TRAILR2/DR5...