ATP7B antibody (AA 1351-1465)

Catalog No. ABIN733433

Product Details anti-ATP7B Antibody

Target: ATP7B (ATPase, Cu++ Transporting, beta Polypeptide (ATP7B))

Binding Specificity: AA 1351-1465

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATP7B antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Pig,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ATP7B

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-ATP7B antibody (ABIN733433)

Wang, Zhu, Zhao, Wang: "miR-133a enhances the sensitivity of Hep-2 cells and vincristine-resistant Hep-2v cells to cisplatin by downregulating ATP7B expression." in: International journal of molecular medicine, Vol. 37, Issue 6, pp. 1636-42, (2016) (PubMed).

Target Details for ATP7B

Target: ATP7B (ATPase, Cu++ Transporting, beta Polypeptide (ATP7B))

Alternative Name: Atp7b (ATP7B Products)

Synonyms: PWD antibody, WC1 antibody, WD antibody, WND antibody, Atp7a antibody, tx antibody, Hts antibody, PINA antibody, Wd antibody, ATP7B antibody, ATPase copper transporting beta antibody, ATPase, Cu++ transporting, beta polypeptide antibody, ATPase, Cu++ transporting, beta polypeptide (Wilson disease) antibody, copper-transporting ATPase 2 antibody, ATP7B antibody, Atp7b antibody, atp7b antibody, LOC592143 antibody

Background:

Synonyms: WD, PWD, WC1, WND, Copper-transporting ATPase 2, Copper pump 2, Wilson disease-associated protein, ATP7B

Background: Involved in the export of copper out of the cells, such as the efflux of hepatic copper into the bile.

Gene ID: 540

UniProt: P35670

Pathways: Transition Metal Ion Homeostasis, Ribonucleoside Biosynthetic Process