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FDCSP antibody (AA 18-85) (Cy5.5)

C4orf7 Reactivity: Human, Mouse IF (cc), IF (p) Host: Rabbit Polyclonal Cy5.5
Catalog No. ABIN734158
  • Target See all FDCSP (C4orf7) Antibodies
    FDCSP (C4orf7) (Chromosome 4 Open Reading Frame 7 (C4orf7))
    Binding Specificity
    • 14
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 18-85
    Reactivity
    Human, Mouse
    Host
    • 19
    Rabbit
    Clonality
    • 19
    Polyclonal
    Conjugate
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FDCSP antibody is conjugated to Cy5.5
    Application
    • 12
    • 12
    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Human, Mouse
    Predicted Reactivity
    Rat,Horse
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from rat FDC-SP
    Isotype
    IgG
    Top Product
    Discover our top product C4orf7 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    FDCSP (C4orf7) (Chromosome 4 Open Reading Frame 7 (C4orf7))
    Alternative Name
    Fdc-Sp (C4orf7 Products)
    Synonyms
    FDC-SP antibody, C4orf7 antibody, cDNA sequence BC037156 antibody, follicular dendritic cell secreted protein antibody, BC037156 antibody, FDCSP antibody
    Background

    Synonyms: FDC, FDCs, Follicular dendritic cell, Follicular dendritic cell secreted protein, Follicular dendritic cell, Follicular dendritic cell secreted peptide, FDC secreted protein.

    Background: Follicular dendritic cells are cells that facilitate antigen recognition by B cells in follicles. This kind of dendritic cell is not bone marrow derived and is not a kind of blood cell. It is purely a resident of the follicles of secondary lymphoid organs. B cells form germinal centers around follicular dendritic cells in lymphoid organs. Dendritic cells form from monocytes, white blood cells which circulate in the body and, depending on the right signal, can turn into dendritic cells or macrophages. The monocytes in turn are formed from stem cells in the bone marrow.In normal tissue this antibody identifies dendritic cells and a proportion of B lymphocytes. Evidence in pathological tissue and functional studies suggests it binds to an epitope expressed by antigen presenting cells. Within the macrophage/dendritic cell populations the epitope seen by RFD1 is coexpressed with RFD7 by a subset of cells that exhibit suppressive activity on T cell stimulation.

    Gene ID
    494224
    UniProt
    Q5R1M6
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