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Antibodies
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anti-Sel-1 Suppressor of Lin-12-Like (C. Elegans) (SEL1L) antibody (PE)
Sel-1 Suppressor of Lin-12-Like (C. Elegans) (SEL1L) antibody (PE)
| Antigen |
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| Synonyms |
IBD2, SEL1L1, PRO1063, SEL1-LIKE, Sel1h, AW493766, KIAA4137, mKIAA4137, SEL1L, MGC99195 |
| Clonality |
Polyclonal |
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Host
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Reactivity
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 Alternatives Human, Mouse (Murine), Rat (Rattus), Pig (Porcine), Cow (Bovine), Rabbit
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Conjugate
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Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
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Application
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| Catalog no. |
ABIN735963 |
| Quantity |
100 µg (1mg/1ml) |
| Price |
330.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 10 to 15 Business Days |
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Alternative name
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SEL1L
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Immunogen
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Polyclonal antibodies are produced by immunizing animals with synthetic peptide derived from human SEL1L
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Format
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Lyophilized
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Reconstitution
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Reconstitute with 100ul sterille distilled water. After reconstitution, stock concentration=1ug/1ul, preservatives included (BSA=10ug/ul, Sodium azide=0.1%)
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Isotype
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IgG
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Description
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Synonym: Suppressor of lin-12-like Protein, IBD2, PRO1063, Sel 1 like protein, Sel 1 suppressor of lin 12 like, SEL1 LIKE, SEL1LIKE, TSA305, AW493766, KIAA4137, mKIAA4137, Sel1h, Sel1l.
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Specificity
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Excitation / Emission Wavelengths: 565nm/578nm
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Molecular Weight
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88kDa
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Comments
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SEL1L highly similar to the C elegans sel-1 gene is a recently cloned human gene whose function is under investigation. SEL1L is differentially expressed in tumors and normal tissues and seems to play a role in tumor growth and aggressiveness. It may be an important negative regulator of the "notch" pathway which acts as a key regulator of the cellular proliferation and specification processes in both vertebrates and invertebrates. SEL1L may function in the protein degradation processes through the ubiquitin-proteosome system and perhaps in regulating important pathways such TGF-beta.. It is ubiquitously expressed only in fetal and neoplastic tissues. In normal adult tissues is highly expressed in the acini and in the alpha cells of the pancreas in general it is highly represented in secretory cells such as plasma cells.
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Application Notes
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Flow-Cyt (1:50-200), IF (1:50-200)
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Concentration
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1mg/1ml
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Purification
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Antibodies are purified by protein A and peptide affinity chromatography.
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Buffer
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0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
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Storage
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Ship at room temperature. Store at -20°C
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Research Area
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Cancer
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Restrictions
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For Research Use only
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Alternatives for antigen "Sel-1 Suppressor of Lin-12-Like (C. Elegans) (SEL1L)", type "Antibodies"
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Hosts
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Rabbit (22), Goat (4)
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Reactivities
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Human (24), Mouse (Murine) (20), Rat (Rattus) (20), Cow (Bovine) (18), Pig (Porcine) (16), Rabbit (15), Dog (Canine) (4), Chicken (2), Horse (Equine) (2), Guinea Pig (1)
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Applications
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Flow Cytometry (FACS) (17), Immunofluorescence (IF) (17), Western Blotting (WB) (9), ELISA (6), Enzyme Immunoassay (EIA) (3), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (2), Immunoprecipitation (IP) (2), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (IHC) (1)
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Conjugates
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Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
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Epitopes
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Center (3)
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